The standardization of terminology of lower urinary tract function in children and adolescents: Report from the standardization committee of the International Children's Continence Society (ICCS)

Nevéus, Tryggve; Gontard, Alexander von; Hjälmås, K; Bauer, Stuart B.; Bower, Wendy; Jørgensen, Troels Munch; Rittig, Søren; Walle, Johan Vande; Yeung, Chung‐Kwong; Djurhuus, Jens Christian

doi:10.1002/nau.20370

Cited by 88 publications

(135 citation statements)

References 30 publications

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“…We agree with others that nocturia once per night is very common in the general population and using the threshold of nocturia ≥2 times per night as LUTS is more appropriate. 2,[17][18][19] Only 2.9% of our control subjects had urgency suggestive of overactive bladder (OAB) according to ICCS definitions, 6 in contrast to 12% of Korean children aged 13 years. 20 Children with OAB may have urinary frequency in addition to urgency.…”

Section: Discussionmentioning

confidence: 91%

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Population-based survey of the prevalence of lower urinary tract symptoms in adolescents with and without psychotropic substance abuse

Tam¹,

Ng²,

Wong³

et al. 2016

Hong Kong Med J

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Objective: To investigate the prevalence of lower urinary tract symptoms in adolescents and the effects of psychotropic substance use. Methods:This was a population-based crosssectional survey using a validated questionnaire in students from 45 secondary schools in Hong Kong randomly selected over the period of January 2012 to January 2014. A total of 11 938 secondary school students (response rate, 74.6%) completed and returned a questionnaire that was eligible for analysis. Individual lower urinary tract symptoms and history of psychotropic substance abuse were documented.Results: In this study, 11 617 non-substance abusers were regarded as control subjects and 321 (2.7%) were psychotropic substance users. Among the control subjects, 2106 (18.5%) had experienced at least one lower urinary tract symptom with urinary frequency being the most prevalent symptom (10.2%). Females had more daytime urinary incontinence (P<0.001) and males had more voiding symptoms (P=0.01). Prevalence of lower urinary tract symptoms increased with age from 13.9% to 25.8% towards young adulthood and age of ≥18 years (P<0.001). Among the substance users, ketamine was most commonly abused. Substance users had significantly more lower urinary tract symptoms than control subjects (P<0.001). In multivariate analysis, increasing age and psychotropic substance population have incurred significant costs to the health care system. In children, the association of LUTS with urinary tract infection, persistent vesicoureteric reflux, renal scarring, and constipation have drawn substantial attention over the years. 3,4 Among various LUTSs, urinary incontinence (UI) has been most extensively investigated in children with the reported prevalence varying from 1.8% to ORIGINAL ARTICLE abuse increased the odds for lower urinary tract symptoms. Non-ketamine substance users and ketamine users were respectively 2.8-fold (95% confidence interval, 2.0-3.9) and 6.2-fold (4.1-9.1) more likely than control subjects to develop lower urinary tract symptoms. Females (odds ratio=9.9; 95% confidence interval, 5.4-18.2) were more likely to develop lower urinary tract symptoms than males (4.2; 2.5-7.1) when ketamine was abused. Conclusions:Lower urinary tract symptoms are prevalent in the general adolescent population. It is important to obtain an accurate history regarding psychotropic substance use when treating teenagers with lower urinary tract symptoms.

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Section: Discussionmentioning

confidence: 91%

“…5 Previous studies of the prevalence of individual LUTS using the International Children's Continence Society (ICCS) definitions 6 have focused primarily on pre-adolescent children in primary schools. [7][8][9][10] To date, no large-scale studies have investigated the prevalence of LUTSs in adolescents.…”

Section: %mentioning

confidence: 99%

Population-based survey of the prevalence of lower urinary tract symptoms in adolescents with and without psychotropic substance abuse

Tam¹,

Ng²,

Wong³

et al. 2016

Hong Kong Med J

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“…Aşırı aktif mesane sendromunda istemsiz detrüsör kasıl-maları izlenmektedir. AAM, yeni ICCS tanımlarında "çocuklarda instabil mesane" tanımının yerine geç-miştir (8) .…”

Section: Aşırı Aktif Mesaneunclassified

Non-neuropathic bladder dysfunctions, and treatment approaches

Tuğtepe¹

2016

tcdd

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“…1 It is defined by the International Children's Continence Society as urinary urgency, with or without incontinence and increased voiding frequency. 2 These symptoms are especially troublesome for pediatric patients and their families. Indeed, it is wellestablished that OAB affects children's well-being, limits everyday activities, and impairs children's development.…”

Section: Introductionmentioning

confidence: 99%

Anticholinergic use in children: Persistence and patterns of therapy

Blais¹,

Bergeron²,

Nadeau³

et al. 2016

CUAJ

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Introduction: Overactive bladder (OAB) symptoms are complex and generally require long-term therapy. Nevertheless, it has been demonstrated that persistence rates of antimuscarinic drug use are low in adults. Better understanding of the treatment patterns of children treated with antimuscarinics could help to improve drug management. Our objective was to evaluate persistence rates of patients under 20 years of age on antimuscarinic therapy over a four-year period. Methods: Patients having received a first-ever antimuscarinic drug prescription between April 2007 and March 2008 were identified using IMS Brogan's Public and Private Drug Plans database. Canadian drug claims data from Private Drug Plans, Régie de l'Assurance Maladie du Québec, and Ontario Public Drug Plans were analyzed retrospectively. Patients were followed for four years to assess the prescribed drugs, the lines of treatment, and the duration of each treatment. Results: Data were available for 374 patients. The most prescribed drug as a first-line therapy was oxybutynin (87.2%), followed by tolterodine LA (5.9%). Patients refilled their index prescriptions for an average of 429 days. Solifenacin had the highest mean duration of index therapy (765 days). The median number of antimuscarinics prescribed was one. At the end of the followup, 44 patients were still on therapy. Reasons for discontinuation of treatment were not available. Conclusions: Overall discontinuation rate of antimuscarinic therapy in children is comparable to what has been reported in adult patients with OAB. However, children seem to persist on the medication for a longer duration before adherence rates start declining. The low rate of persistence highlights the need to identify the reasons for discontinuation of therapy in children in order to obtain better persistence rates.

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The standardization of terminology of lower urinary tract function in children and adolescents: Report from the standardization committee of the International Children's Continence Society (ICCS)

Cited by 88 publications

References 30 publications

Population-based survey of the prevalence of lower urinary tract symptoms in adolescents with and without psychotropic substance abuse

Population-based survey of the prevalence of lower urinary tract symptoms in adolescents with and without psychotropic substance abuse

Non-neuropathic bladder dysfunctions, and treatment approaches

Anticholinergic use in children: Persistence and patterns of therapy

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