Every day, employees in the lodging and hospitality industry are potentially exposed to bloodborne pathogens and other infectious diseases. Federally sponsored biosafety and infectious disease training sessions were conducted at two lodging sites in an effort to promote infectious disease primary prevention, as well as mitigation and management techniques in the hospitality industry in an effort to develop interdisciplinary connections between public health and hospitality. The trainings were positively received, but as this viewpoint reveals, further research, partnerships, and curriculum development is needed in this area in order for it to have long-term and impactful effects.