Background: Various initiatives are underway to improve maternal satisfaction with the vaccination of children in developing nations. Governments, international organizations, and nongovernmental organizations are actively working to improve healthcare infrastructure, expand service accessibility, improve communication, and foster community engagement. However, despite these efforts, maternal satisfaction with child vaccination services continues to be a significant issue.Objective: This systematic review and meta‐analysis is aimed at assessing the pooled prevalence of maternal satisfaction with the child’s vaccination service and its predictors in Ethiopia.Methods: Scopus, Embase, Web of Science, Google Scholar, PubMed, African Journals Online, and Semantic Scholar were searched to access the included articles. A weighted inverse‐variance random effect model was used to estimate the prevalence of maternal satisfaction with vaccination of children. Variations in pooled prevalence estimates were adjusted by subgroup analysis according to the specific region where the study was conducted. Funnel plot and Egger’s regression test were used to check publication bias. STATA version 14 statistical software was used for meta‐analysis.Results: The combined prevalence of maternal satisfaction with vaccination of children was found to be 73% (95% CI: 72–75; I2 = 0.00%, p value < 0.001). Based on the subgroup analysis, the result revealed that the prevalence of maternal satisfaction with vaccination of children was 63% in SNNPR, 79% in Oromia, and 74% in Amhara.Conclusions: A meta‐analysis of mothers’ satisfaction with vaccination services for their children in Ethiopia found a low level of satisfaction. Therefore, provide regular training and capacity‐building programs for healthcare workers involved in the delivery of vaccination services.