2004
DOI: 10.1159/000078752
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The Stent-Supported Percutaneous Angioplasty of the Carotid Artery vs. Endarterectomy Trial

Abstract: The Stent-Supported Percutaneous Angioplasty of the Carotid Artery versus Endarterectomy (SPACE) Trial is investigating if both treatment modalities are equivalent in the treatment of severe symptomatic carotid stenoses. Patients with symptomatic (transient ischaemic attack or minor stroke) stenosis (above 50% following the North American Symptomatic Endarterectomy Trial criteria) eligible for both methods can be recruited into this trial. The primary endpoint is the incidence of an ipsilateral stroke or death… Show more

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Cited by 81 publications
(41 citation statements)
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“…We are aware of 4 trials currently ongoing comparing carotid endovascular treatment with endarterectomy: the International Carotid Stenting Study (ICSS), 33 Carotid Revascularization Endarterectomy versus Stenting Trial (CREST), 34 Stent-protected Percutaneous Angioplasty of the Carotid versus Endarterectomy (SPACE), 35 and Endarterectomy versus Angioplasty in patients with Severe Symptomatic Stenosis (EVA-3S). 36 Table 2 shows the rates of outcome events for each of the included studies.…”
Section: Ongoing Trialsmentioning
confidence: 99%
“…We are aware of 4 trials currently ongoing comparing carotid endovascular treatment with endarterectomy: the International Carotid Stenting Study (ICSS), 33 Carotid Revascularization Endarterectomy versus Stenting Trial (CREST), 34 Stent-protected Percutaneous Angioplasty of the Carotid versus Endarterectomy (SPACE), 35 and Endarterectomy versus Angioplasty in patients with Severe Symptomatic Stenosis (EVA-3S). 36 Table 2 shows the rates of outcome events for each of the included studies.…”
Section: Ongoing Trialsmentioning
confidence: 99%
“…The protocols in two other ongoing trials do not require cerebral protection; however, these devices may be used at the discretion of the physician. 10,19 The aforementioned trials include the International Carotid Stenting Study (CAVATAS-2) and the Stent Protected Angioplasty versus Carotid Endarterectomy trial.…”
Section: Neurosurg Focus / Volume 18 / January 2005mentioning
confidence: 99%
“…[66]). Aus den aktuellen Studien zur stentgeschützten Angioplastie (SPACE, EVA3S, ICCS) sind Patienten mit im Vergleich zur Bifurkationsstenose höhergradiger intracranieller Stenose ausgeschlossen worden [91].…”
Section: Methodenkritikunclassified