The stereochemistry of thuriferic and epithuriferic acids

The synthesis of a 1‐aryltetralin privileged structure‐based library of novel angular heterocyclic lignans is described. Indolotetralins 3, tetrahydroquinolinotetralins 4, and thiochromanotetralins 5 were obtained from the methyl ester of thuriferic acid 2 according to a three‐step procedure involving an InCl3‐catalyzed Friedel–Crafts‐type cyclization as the key step.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

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Synthesis of Novel Angular Heterocyclic Lignans by an InCl₃‐Catalyzed Friedel–Crafts‐Type Cyclization

Dorbec

Florent

Monneret

et al. 2008

Eur J Org Chem

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Syntheses of (±)-thuriferic acid ethyl ester, its analogues and (±)-picropodophyllone

et al. 2005

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Correct structures of Diels–Alder adducts from the natural cyclolignan thuriferic acid and its 8-epimer

et al. 2006

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The stereochemistry of thuriferic and epithuriferic acids

Cited by 10 publications

References 13 publications

Synthesis of Novel Angular Heterocyclic Lignans by an InCl₃‐Catalyzed Friedel–Crafts‐Type Cyclization

Synthesis of Novel Angular Heterocyclic Lignans by an InCl₃‐Catalyzed Friedel–Crafts‐Type Cyclization

Syntheses of (±)-thuriferic acid ethyl ester, its analogues and (±)-picropodophyllone

Correct structures of Diels–Alder adducts from the natural cyclolignan thuriferic acid and its 8-epimer

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The stereochemistry of thuriferic and epithuriferic acids

Cited by 10 publications

References 13 publications

Synthesis of Novel Angular Heterocyclic Lignans by an InCl3‐Catalyzed Friedel–Crafts‐Type Cyclization

Synthesis of Novel Angular Heterocyclic Lignans by an InCl3‐Catalyzed Friedel–Crafts‐Type Cyclization

Syntheses of (±)-thuriferic acid ethyl ester, its analogues and (±)-picropodophyllone

Correct structures of Diels–Alder adducts from the natural cyclolignan thuriferic acid and its 8-epimer

Contact Info

Product

Resources

About

Synthesis of Novel Angular Heterocyclic Lignans by an InCl₃‐Catalyzed Friedel–Crafts‐Type Cyclization

Synthesis of Novel Angular Heterocyclic Lignans by an InCl₃‐Catalyzed Friedel–Crafts‐Type Cyclization