The stimulation of follicular growth in cultured mouse ovaries by lactate salts

Abstract

When intact ovaries of infantile mice are cultured in the presence of gonadotrophins, steroids or dibutyryl cyclic adenosine 3':5' monophosphate follicular growth is stimulated. If [3H]thymidine is supplied in the medium, its accumulation in the tissue is enhanced as a result of this growth (Ryle, 1969(Ryle, , 1972(Ryle, , 1974Kent, 1973