The Batang Merao Watershed, has been experiencing a decline in water quality due to human activities involving waste utilization and disposal. Therefore, an analysis is necessary to determine the Total Maximum Daily Loads (TMDLs). This study aims to calculate the TMDL of the Batang Merao Watershed and the current as well as the five-year future pollution load capacity using the QUAL2Kw water quality model based on the regulations outlined in the Minister of Environment and Forestry's Regulation No. 01 of 2010. The calibration results of the model using the Nash Sutcliffe Efficiency (NSE) for TSS, BOD5, and COD parameters were 0.766, 0.574, and 0.633, respectively, indicating that water quality modeling can be used to predict river pollution loads. The modeling results indicate that the Total Maximum Daily Loads (TMDLs) for the Batang Merao Watershed are 95,057 kg day-1 for TSS parameters, 5,739 kg day-1 for BOD5 parameters, and 46,774 kg day-1 for COD parameter. Meanwhile, the current pollution loads are 147,962 kg day-1 for TSS, 10,086 kg day-1 for BOD5, and 60,369 kg day-1 for COD. In the estimated condition, in the year 2028, the pollution loads will amount to 163,023 kg day-1 for TSS parameters, 11,432 kg day-1 for BOD5 parameter, and 69,211 kg day-1 for COD parameter.