2022
DOI: 10.1101/2022.10.06.511163
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The striatum drives the ergogenic effects of caffeine

Abstract: Caffeine is one of the main ergogenic resources used in exercise and sports. Previously, we presented the ergogenic mechanism of caffeine through neuronal A2AR antagonism in the central nervous system [1]. We demonstrate here that the striatum rules the ergogenic effects of caffeine through neuroplasticity changes. Thirty-four Swiss (8-10 weeks, 47 ± 1.5 g) and twenty-four C57BL6 (8-10 weeks, 23.9 ± 0.4 g) adult male mice were challenged in behavior and electrophysiology experiments using caffeine and SH-SY5Y … Show more

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Cited by 2 publications
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