The Structural Properties of an Osteochondral Cylinder Graft-Recipient Construct on Autologous Osteochondral Transplantation

Abstract

Care should be taken when planning the rehabilitation program at an early phase after osteochondral transplantation.

The effect of fibroblast growth factor-2 on autologous osteochondral transplantation

“…We previously reported decreased stiffness at postoperative weeks 1, 3 and 8 compared to normal cartilage stiffness. The stiffness at postoperative week 3 was the lowest, suggesting that subchondral bone formation and remodelling influences the changes of cartilage stiffness [14] and similar results were found in this study; that is, the stiffness of the transplanted grafts decreased the most at postoperative week 3 in Group III. At postoperative week 3, the average stiffness in Group I was significantly greater than that in Group III.…”

“…In contrast, changes in the mechanical properties of the transplanted osteochondral graft have been analysed in various autologous osteochondral transplantation models and evaluated at various periods after surgery [9,10,15,28]. We previously demonstrated that the structural properties of an osteochondral cylinder-graftrecipient construct immediately after surgery are not significantly different from those of normal cartilage and that the structural properties of an osteochondral cylindergraft-recipient reconstruction are significantly worse at postoperative weeks 1 through 8 than in normal cartilage [14]. We speculated that changes in the structural properties of the transplanted osteochondral graft are influenced by the healing process at the subchondral bone level.…”

Osteochondral Resurfacing (OCRPRC) for Capitate Chondrosis in Proximal Row Carpectomy

“…This has been proven in rabbit, ovine, and porcine models at time points to as far as 1 year after transplantation. [22][23][24][25][26][27][28] In addition to the knee, osteochondral grafting has been used in the capitellum, talus, and femoral head with graft viability being proven with second-look arthroscopy, MRI, and biopsy. 29 -34 Barber in 1991 showed that osteochondral grafts maintained their integrity, and living chondrocytes and osteocytes in the grafts were found at 12 months after implantation.…”

Technique: Osteochondral Grafting of Capitate Chondrosis in PRC

“…23 In multiple studies including rabbit, ovine, and porcine models, chondrocytes and osteocytes of the osteochondral graft have been shown to survive transplantation. [24][25][26][27][28][29][30] Osteochondral grafting has also been used in the capitellum, talus, and femoral head, with graft viability proven with second-look arthroscopy, MRI, and biopsy. [31][32][33][34][35][36][37] The MRI of our patient at 21 months postoperative showed bone incorporation of the graft to the capitate and the presence of graft cartilage (►Fig.…”