Posttraumatic stress disorder (PTSD) is a chronic and disabling reaction to extreme stress. Because of the strong consequences of long-lasting PTSD symptoms, the research of risk and protective factors is needed. Presented meta-analysis aimed to verify temperament traits according to the Regulative Theory of Temperament as risk/protective factors of PTSD symptoms development. The studies for this meta-analysis were found in four main databases of scientific journals and due to contact with first authors, the unpublished data was accessed as well. The inclusion criteria allowed studies with traumatized adult populations and operationalization of the temperament according to the Regulative Theory of Temperament. Finally, data were included from 19 studies (5971 people: 3443 men and 2528 females, in the age of 13-85) with prospective, longitudinal and cross-sectional study designs, carried out among people exposed to combat trauma, occupational trauma (policemen and fire-fighters), disasters (flood, fire and mining catastrophes), motor vehicle accidents and chronic illnesses. The results show significant moderate and weak relations of all temperament traits to PTSD symptoms regardless of people’s gender, type of study, type of trauma, DSM version and temperament measure as well as the time elapsed after the trauma. Among different moderators, a previously unrecognized effect of gender was revealed as it explained a significant amount of variance in the case of emotional reactivity, endurance, and perseveration - the relationship was significantly stronger among men than women. Methodological conclusions for further research on personality and trauma are drawn.