The Study of Body Weight, Haematological and Serum Biochemical Parameters, Liver and Kidney Texture in Rats Fed Corn Oil

doi:10.21271/zjpas.29.s4.8

Cited by 2 publications

(1 citation statement)

References 19 publications

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“…Corn Oil has been concluded to be a potent antioxidant agent from results of chemical assays 12 . Another study on the body weight, biochemical, and haematological parameters have also proved the capability of corn oil has on the liver and kidneys of rats, further highlighting its antioxidant prowess 13 . Otuechere et al (2014) in a study conducted by him showed that coconut oil had a protective effects against the toxic nature of Trimethoprim-sulfamethoxazole (TMP-SMX) a broad spectrum antibiotic used to treat gram-positive and gram-negative aerobic infections induced a positive effect on the livers of rats.…”

Section: Discussionmentioning

confidence: 85%

Restoration of Germinal Epithelium with Usage of Antioxidant Oils in Phenytoin Induced Testicular Toxicity: A Comparative Study in Rats

Rehman,

Ali,

Shehzad

et al. 2023

J. Bahria Uni. Med. Dent. Coll.

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Objective: To evaluate antioxidant effect of Virgin Coconut Oil (VCO) and Corn Oil (CO) on germinal thickness (GT) in rats induced with phenytoin toxicity. Study design and setting: An Experimental Longitudinal study was done at AL-Tibri Medical College and Hospital Isra University Karachi Campus. Methodology: 28 male albino rats were selected and were divided into 4 groups each consisting of 7 rats. Group A received normal saline solution only, Group B received 10mg/kg/body weight of Phenytoin, Group C received VCO+ Phenytoin, and Group D received CO+ Phenytoin. Animals were euthanized on the 4th, 5th, & 6th week and tissue sample was acollected for measuring GT using stage micrometer. Data was analyzed using SPSS 20.0. All values were expressed as mean ± S.D., groups compared using One way ANOVA followed by Post hoc Tukey’s test with p- value <0.05. Results: on 4th, 5th, & 6th week significant difference in germinal thickness was seen in Group A comparing it against the phenytoin group B (P-value: <0.001, <0.001, & 0.001). On 4th, 5th, & 6th week significant difference in GT was seen in Group C (VCO + Phenytoin) comparing it against the phenytoin group B (P-value: <0.001, <0.001, &< 0.001). No significant difference in germinal thickness was seen on 4th, 5th, & 6th week was seen when Group D (CO + Phenytoin) was compared to Group B (p-value: 0.551, 0.954, & 0.931). Conclusion: Virgin Coconut Oil can reduce the negative effect caused by phenytoin induced toxicity by preventing thinning of the germinal layer.

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Section: Discussionmentioning

confidence: 85%

Restoration of Germinal Epithelium with Usage of Antioxidant Oils in Phenytoin Induced Testicular Toxicity: A Comparative Study in Rats

Rehman,

Ali,

Shehzad

et al. 2023

J. Bahria Uni. Med. Dent. Coll.

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Effect of Different Dietary Oils and Fat on Body Weight, Food Intake, Some Haematological and Biochemical Parameters in Female Albino Rats

Abdullah¹,

Rasoul²,

Mahmood³

2018

KJAR

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The present study investigates the influence of different dietary plant oils included sunflower oil (SO), olive oil (OO) corn oil (CO), and animal (AF) on different parameters in female albino rats. Twenty-two animals were divided equally and randomly into five groups, the treatment was performed by needle gavage. First group fed on basal diet and served as control. Second group fed on a basal diet with 0.3ml/rat animal fat orally. Third group fed on a basal diet with 0.3ml/rat sunflower oil orally. Fourth group fed on a basal diet with 0.3ml/rat olive oil orally. Fifth group fed on a basal diet with 0.3ml/rat corn oil orally. It continued for 28 days. Several parameters were measured during and after the study such as body weight, food intake, organ weight (kidney, liver and spleen) Haematological parameters (Hb, RBC, WBC, PLT, HCT and MCV), lipid profile (Total cholesterol, TG, HDL and LDL). Commonly plant oils and animal fat showed both benefits and harmful effects on the mentioned parameters; the corn oil and olive oil played important role through generating the healthy signs among other oils and animal fat. The present results concluded that both corn oil and olive oil may own positive effect than the other animal fat sunflower oil of people used in their daily diet.

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The Study of Body Weight, Haematological and Serum Biochemical Parameters, Liver and Kidney Texture in Rats Fed Corn Oil

Cited by 2 publications

References 19 publications

Restoration of Germinal Epithelium with Usage of Antioxidant Oils in Phenytoin Induced Testicular Toxicity: A Comparative Study in Rats

Restoration of Germinal Epithelium with Usage of Antioxidant Oils in Phenytoin Induced Testicular Toxicity: A Comparative Study in Rats

Effect of Different Dietary Oils and Fat on Body Weight, Food Intake, Some Haematological and Biochemical Parameters in Female Albino Rats

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