The study of the inhibitory effect of calcium oxalate monohydrate's crystallization by two medicinal and aromatic plants: Ammi visnaga and Punica granatum

Chemical Compounds Identification and Antioxidant and Calcium Oxalate Anticrystallization Activities of Punica granatum L.

“…In addition, the image analysis relating to this phase ( Figure 5(b)) exhibits the presence of larger and more numerous aggregates in the absence of inhibitor, while the size and the number of crystals become less important in the case of the treatment, especiallyE.PG and the I.PG. Moreover, the results of this study are more important than our subsequent results on crude methanolic extracts of the same plant and those of Ammi visnaga [55], as well as the hydroethanolic extract and the infusion of A. unedo leaves [41]. Similarly, they far exceed those of Sharma et al [70] who worked on the aqueous extract of the Chenopodium album leaves and Cystone.…”

“…Nevertheless, the analysis of the images taken during this phase ( Figure 5(a)) displays that the number and the size become less important in presence of the extracts of E.PG, I.PG, and Cit.K solution. is reflects the results of the turbidity concentrations of 0.5, 1, and 2 g/L, while the Cit.K solution shows a less important effect than the two extracts, with inhibition rate of 68.25 ± 2.4, 69.70 ± 2.85, and 77.12 ± 2.16% (R > 0.95, CV < 10%) for the same concentrations [55]. In addition, the image analysis relating to this phase ( Figure 5(b)) exhibits the presence of larger and more numerous aggregates in the absence of inhibitor, while the size and the number of crystals become less important in the case of the treatment, especiallyE.PG and the I.PG.…”

“…e analysis of the data in Table 4 shows a high efficiency of the two plant extracts in a dose-dependent manner in inhibiting the nucleation of calcium oxalate crystals. In fact, the inhibition percentages are in order of 93.38 ± 0.09, 94.97 ± 0.21, and 98.11 ± 0.17% (P < 0.05 vs. Cit.K) (R > 0.95, CV < 10%) for E.PG at concentrations of 0.5, 1, and 2 g/L, respectively, and in the order of 93.01 ± 1.22% (P < 0.05 vs. Cit.K), 97.59 ± 0.30, and 98.22 ± 0.71% (R > 0.95, CV < 10%) for I.PG at concentrations of 0.5, 1, and 2 g/L, respectively, whereas, for potassium citrate (Cit.K) taken as a positive control, the values found are in the order of 96.52 ± 0.01, 97.01 ± 0.06, and 97.37 ± 0.16% (R > 0.95, CV < 10%) at concentrations of 0.5, 1, and 2 g/L, respectively [55]. Nevertheless, the analysis of the images taken during this phase ( Figure 5(a)) displays that the number and the size become less important in presence of the extracts of E.PG, I.PG, and Cit.K solution.…”

“…e anticrystallization effect of the plant extracts has been studied according to the protocol described by Hess et al [54] and repeated by Kachkoul et al [41,55]. e stock solutions of CaCl 2 : 2H 2 O [15 mM] and Na 2 C 2 O 4 [1.5 mM] containing NaCl [200 mM] have been prepared, to which 10 mM sodium acetate was added to adjust the pH value to 5.7.…”

Plant Extracts in Hyperoxaluria Treatment: A Review of Experimental and Clinical Research

“…The vegetable extracts such as Holarrhena antidysenterica, Origanum vulgare and Terminalia chebula can inhibit cell damage, preferably by inhibiting free radicals. [28][29][30][31] Protective action of Paronychia argentea, B. ligulata, Quercus salieina, Achyranthus Aspera and Ammi visnaga also occurs due to stimulation of antioxidant activity. [23,31,32] The effects of the main plant extracts are given in Table 1.…”