The study aimed to investigate elementary and secondary school teacher's knowledge, attitude, and self-efficacy regarding cardiopulmonary resuscitation (CPR), and explore which factors affect their intention to perform CPR. Methods: A descriptive correlational study design was utilized. Data were collected using self-reported questionnaire from 147 teachers. Statistical analysis was conducted using descriptive statistics, t-test, x 2 test, F-test, Pearson correlation coefficients, and logistic regression with the SPSS/WIN 21.0 program. Results: The average of knowledge, attitude and self-efficacy on CPR was 11.11±1.88 out of 15, 42.81±5.22 out of 55, and 86.19±17.74 out of 120 in order. CPR performance intention had significantly positive correlations with knowledge, attitude, and self-efficacy on CPR. In logistic regression, factors significantly affecting intention to perform CPR were the total number of training sessions on CPR (OR=12.15, 95% CI: 2.83~52.20), attitude on CPR (OR=9.26, 95% CI: 1.61~53.34), and self-efficacy on CPR (OR=1.72, 95% CI: 1.04~2.84), which accounted for 42.7% of the variance. Conclusion: In order to increase the intention to perform CPR among teachers in elementary and secondary schools, it is necessary for an educational program to be developed to improve positive attitudes and self-efficacy on CPR.