OBJECTIVE-The purpose of this study was to determine the effect of maternal superobesity (body mass index [BMI], ≥50 kg/m 2 ) compared with morbid obesity (BMI,(40)(41)(42)(43)(44)(45)(46)(47)(48)(49).9 kg/m 2 ) or obesity (BMI, kg/m 2 ) on perinatal outcomes.STUDY DESIGN-We conducted a retrospective cohort study of birth records that were linked to hospital discharge data for all liveborn singleton term infants who were born to obese Missouri residents from 2000-2006. We excluded major congenital anomalies and women with diabetes mellitus or chronic hypertension.RESULTS-There were 64,272 births that met the study criteria, which included 1185 superobese mothers (1.8%). Superobese women were significantly more likely than obese women to have preeclampsia (adjusted relative risk [aRR], 1.7; 95% confidence interval [CI], 1.4 -2.1), macrosomia (aRR, 1.8; 95% CI, 1.3-2.5), and cesarean delivery (aRR, 1.8; 95% CI, 1.5-2.1). Almost one-half of all superobese women (49.1%) delivered by cesarean section, and 33.8% of superobese nulliparous women underwent scheduled primary cesarean delivery.CONCLUSION-Women with a BMI of ≥50 kg/m 2 are at significantly increased risk for perinatal complications compared with obese women with a lower BMI.
Keywords pregnancy outcome; superobesityThe obesity epidemic remains unabated in the United States. In 2007-2008 of American women who were 20-39 years old met obesity criteria (body mass index [BMI] ≥30 kg/m 2 ) 1 ; obesity is now an increasingly common and harmful pregnancy complication. Superobesity, as coined in the gastric bypass literature to describe patients who weigh ≥225% of ideal body weight, 2 represents individuals with a BMI of ≥50 kg/m 2 . The number of superobese individuals is growing 5 times faster than other obesity categories, 3 which means that healthcare providers increasingly will be challenged to accommodate their healthcare needs. Presented as a poster at the 31st annual meeting of the Society for Maternal-Fetal Medicine, San Francisco, CA, Feb. 7-12, 2011. NIH Public Access Obese women are more likely than normal weight women to experience preeclampsia, diabetes mellitus, cesarean delivery, fetal growth abnormalities, and stillbirth. 4 Although several studies compare obese women to normal-weight women, to date there have been limited studies on superobesity in pregnancy. [5][6][7] As the number of superobese pregnant women continues to rise, it is important to determine whether there is a "dose-response" relationship between the severity of maternal obesity and perinatal complications.The objective of this study was to determine the effect of maternal superobesity on perinatal outcomes compared with maternal obesity (BMI, 30-39.9 kg/m 2 ) and morbid obesity (BMI,(40)(41)(42)(43)(44)(45)(46)(47)(48)(49).9 kg/m 2 ). We hypothesized that pregnancy in super-obese women, compared with obese and morbidly obese women, is associated with (1) increased risk of maternal complications of pregnancy, (2) greater risk of fetal growth abnormalities, and (3) grea...