Corrosion processes of strings on musical instruments occur frequently. Such processes significantly influence sound quality, but also human health because metals may provoke skin allergy. Therefore, in this study the corrosion process of six guitar strings and metal ions release associated with nickel allergy was monitored after immersion in sweat solution for 28 days. Dissolution of metal ions was measured as a function of time, and the changes of the samples after 28 days were studied by SEM/EDS. The results have shown that the amounts of dissolved metal ions in corrosive solution are decreasing in the following order: Fe 3þ < Sn 2þ < Mn 2þ < Si 4þ < Ni 2þ . The corrosion of electric guitar strings in artificial sweat solution was determined by the solubility of samples. The electric guitar strings E6, A5 and D4 corrosion kinetic in artificial sweat followed parabolic rate relation, while g3, h2 and e1 strings followed linear rate relation. After the 4 weeks of monitoring, the quantities of the nickel eluted ions did not exceed the limits prescribed by standard regulations. Therefore, such items do not present a threat to human health.