The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection

Mazuski, John E.; Tessier, Jeffrey M.; May, Addison K.; Sawyer, Robert G.; Nadler, Evan P.; Rosengart, Matthew R.; Chang, Pei Ching; O’Neill, Patrick J.; Mollen, Kevin P.; Huston, Jared M.; Diaz, José J.; Prince, José M.

doi:10.1089/sur.2016.261

Cited by 454 publications

(478 citation statements)

References 660 publications

(1,590 reference statements)

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“…The SIS‐NA/IDSA 2010 guidelines recommended against routine blood cultures for community‐acquired intra‐abdominal infections since the results do not change the management and outcomes . This recommendation is carried forward in recent guidelines . This is in part driven by a study of the clinical impact of blood cultures taken in the emergency department .…”

Section: Clinical Questionsmentioning

confidence: 99%

“…Especially, extended‐spectrum beta‐lactamases (ESBL) and carbapenemases (i.e. metallo‐beta‐lactamase and non‐metallo‐beta‐lactamase) producing bacilli reported have been significantly affecting the selection of empirical therapy for patients with intra‐abdominal infections, including acute cholangitis and cholecystitis .…”

Section: Introductionmentioning

confidence: 99%

“… Ampicillin/sulbactam has little activity left against Escherichia coli . It is removed from the North American guidelines …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Tokyo Guidelines 2018: antimicrobial therapy for acute cholangitis and cholecystitis

Gomi

Solomkin

Schlossberg

et al. 2018

J Hepato Biliary Pancreat

297

249

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Antimicrobial therapy is a mainstay of the management for patients with acute cholangitis and/or cholecystitis. The Tokyo Guidelines 2018 (TG18) provides recommendations for the appropriate use of antimicrobials for community-acquired and healthcare-associated infections. The listed agents are for empirical therapy provided before the infecting isolates are identified. Antimicrobial agents are listed by classdefinitions and TG18 severity grade I, II, and III subcategorized by clinical settings. In the era of emerging and increasing antimicrobial resistance, monitoring and updating local antibiograms is underscored. Prudent antimicrobial usage and early de-escalation or termination of antimicrobial therapy are now important parts of decision-making. What is new in TG18 is that the duration of antimicrobial therapy for both acute cholangitis and cholecystitis is systematically reviewed. Prophylactic antimicrobial usage for elective endoscopic retrograde cholangiopancreatography is no longer recommended and the section was deleted in TG18. Free full articles and mobile app of TG18 are available at: http://www.jshbps.jp/modules/en/index.php?content_id=47. Related clinical questions and references are also included.

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Section: Clinical Questionsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Tokyo Guidelines 2018: antimicrobial therapy for acute cholangitis and cholecystitis

Gomi

Solomkin

Schlossberg

et al. 2018

J Hepato Biliary Pancreat

297

249

View full text Add to dashboard Cite

show abstract

“…All four guidelines recommend performing intra‐abdominal cultures in high‐risk patients and those with healthcare‐associated CIAI. However, for low‐risk patients with community‐acquired CIAI, one guideline recommends not taking intra‐abdominal cultures and others have equivocal or no recommendations. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 state that various specimens, including blood, may be collected for culture from patients with sepsis or septic shock as considered necessary.…”

Section: Discussionmentioning

confidence: 99%

Nationwide observational study of mortality from complicated intra-abdominal infections and the role of bacterial cultures

Tsuchiya

Yasunaga

Tsutsumi

et al. 2019

British Journal of Surgery

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Background: The benefit of taking intra-abdominal cultures during source control procedures in patients with complicated intra-abdominal infection (CIAI) is unknown. The aim of this study was to evaluate whether intra-abdominal cultures reduce the mortality rate of CIAI.Methods: The Japanese Diagnosis Procedure Combination database was used to identify adult patients with CIAI who had undergone source control procedures on the first day of admission to hospital between April 2014 and March 2016. In-hospital mortality was compared between patients who did and those who did not have intra-abdominal cultures taken. A generalized linear mixed-effect logistic regression model and a random intercept per hospital were used to adjust for baseline confounders and institutional differences. Subgroup analyses were also performed according to disease cause, site of onset and severity of CIAI. Results: Intra-abdominal cultures were taken from 16 303 of 41 495 included patients. Multivariable logistic regression analysis showed that patients with intra-abdominal cultures had a significantly lower mortality than those without (odds ratio 0⋅85, 95 per cent c.i. 0⋅77 to 0⋅95). Subgroup analyses revealed statistically significant differences in mortality between patients with and without cultures among those with lower intestinal perforation, biliary tract infection/perforation, healthcare-associated CIAI and high-risk community-acquired CIAI.Conclusions: Intra-abdominal cultures obtained during source control procedures may reduce in-hospital mortality, especially in patients with lower intestinal perforation, biliary tract infection/perforation, or healthcare-associated or high-risk community-acquired CIAI.

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“…Третичный перитонит является рецидивирующей инфекцией брюшной полости, которая возникает через 48 часов после адек-ватной санации вторичного перитонита. Часто встречается у критических пациентов, пациентов с ослабленным иммунитетом, ассоциируется с мультирезистентными штаммами микроорганиз-мов [3,4].…”

Section: научный обзор / Scientific Reviewunclassified

Інтраабдомінальна Інфекція У Світлі Останніх Міжнародних Рекомендацій Та Її Роль У Розвитку Септичної Енцефалопатії

Maltseva¹,

Мосенцев²,

Lisnycha³

2021

ЕМ

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Мета цих рекомендацій: представити міжнародну позицію, засновану на доказах, із питань застосування методів ведення внутрішньоабдомінальних інфекцій та вплив внутрішньоабдомінальних інфекцій на розвиток септичної енцефалопатії. Ускладнена інтраабдомінальна інфекція є важливою причиною захворюваності та смертності. В уявленні Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) сепсис визначається як загрозлива для життя дисфункція органа, що викликана дисрегуляторною відповіддю хазяїна на інфекцію. Дисфункція органа може бути подана як збільшення показника на більше ніж 2 бала за шкалою Sequential Organ Failure Assessment (SOFA). Раннє виявлення пацієнтів з абдомінальним сепсисом є важливим кроком для ефективного лікування з метою покращання результатів. Мікросудинна дисфункція, глобальне пошкодження тканин можуть призвести до розвитку септичної енцефалопатії, що асоціюється з поганим прогнозом. Ключовими факторами ефективної терапії внутрішньоабдомінальних інфекцій є оперативний діагноз, адекватна реанімація, ранній початок відповідної антибактеріальної терапії, ранній контроль джерела інфекції та постійна переоцінка клінічної відповіді на тактику ведення. Оцінка ефективності рекомендацій та якості доказів подані відповідно до Grading of Recommendations Assessment, Development and Evaluation (GRADE).

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The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection

Abstract: The current recommendations of the SIS regarding the treatment of patients with IAI are provided in this guideline.

Cited by 454 publications

References 660 publications

Tokyo Guidelines 2018: antimicrobial therapy for acute cholangitis and cholecystitis

Tokyo Guidelines 2018: antimicrobial therapy for acute cholangitis and cholecystitis

Nationwide observational study of mortality from complicated intra-abdominal infections and the role of bacterial cultures

Інтраабдомінальна Інфекція У Світлі Останніх Міжнародних Рекомендацій Та Її Роль У Розвитку Септичної Енцефалопатії

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