The Surgical Management of Sacrococcygeal Teratomas with Intrapelvic Extension

Hendren, W. Hardy; Henderson, Bruce M.

doi:10.1097/00000658-197001000-00012

Cited by 39 publications

(12 citation statements)

References 4 publications

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“…The sacrococcygeal area is the most frequent of sites for teratomas in infancy (Berry, Keeling & Hilton 1969, Hendren & Henderson 1970. They are, however, rare tumours, their incidence being reported as 1 in 35000 births (Calbet 1893) and 1 in 40000 births (Dillard et al 1954).…”

Section: Discussionmentioning

confidence: 99%

Malignant sacrococcygeal teratoma in the adult

Ahmed

Pollock

1985

Histopathology

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Section: Discussionmentioning

confidence: 99%

Malignant sacrococcygeal teratoma in the adult

Ahmed

Pollock

1985

Histopathology

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“…There are reports of very rare tumors that occupy hematopoietic spaces such as grade IV sacrococcygeal tumors of the pelvis (279,280). As mentioned earlier, adult sacrococcygeal tumors are very rare, though intrapelvic presentations may predominate in older patients (267).…”

Section: Germ Cell Tumors Of the Fetus Children And Adultsmentioning

confidence: 97%

Pluripotent stem cells and their niches

2006

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The ability of stem cells to self-renew and to replace mature cells is fundamental to ontogeny and tissue regeneration. Stem cells of the adult organism can be categorized as mono-, bi-, or multipotent, based on the number of mature cell types to which they can give rise. In contrast, pluripotent stem cells of the early embryo have the ability to form every cell type of the adult body. Permanent lines of pluripotent stem cells have been derived from preimplantation embryos (embryonic stem cells), fetal primordial germ cells (embryonic germ cells), and malignant teratocarcinomas (embryonal carcinoma cells). Cultured pluripotent stem cells can easily be manipulated genetically, and they can be matured into adult-type stem cells and terminally differentiated cell types in vitro, thereby, providing powerful model systems for the study of mammalian embryogenesis and disease processes. In addition, human embryonic stem cell lines hold great promise for the development of novel regenerative therapies. To fully utilize the potential of these cells, we must first understand the mechanisms that control pluripotent stem cell fate and function. In recent decades, the microenvironment or niche has emerged as particularly critical for stem cell regulation. In this article, we review how pluripotent stem cell signal transduction mechanisms and transcription factor circuitries integrate information provided by the microenvironment. In addition, we consider the potential existence and location of adult pluripotent stem cell niches, based on the notion that a revealing feature indicating the presence of stem cells in a given tissue is the occurrence of tumors whose characteristics reflect the normal developmental potential of the cognate stem cells.

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“…The abdominosacral approach has been reported by both Localio et alii (1 967) and MacCarty et alii (1961) for the removal of the large chordoma. It is used by some paediatric surgeons in the surgical management of the abdominal extension of the sacrococcygeal teratoma (Hendren and Henderson, 1970). The combined approach is always available and is of undoubted value in the presence of an extensive neoplasm.…”

Section: Surgerymentioning

confidence: 99%

Postrectal Neoplasms and Cysts

Johnson

1980

Australian and New Zealand Journal of Surgery

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The postrectal space is extensive and is in relationship to the sacral promontory and sacrum above and the coccyx below. Any of the structures in or adjacent to the space may be involved by or give rise to a postrectal neoplasm. In addition, a group of congenital neoplasms and cysts may also present in this space. Uhlig and Johnson in 1975 reviewed patients presenting to hospitals in the Portland, Oregon, U.S.A. area over a 25‐year period. The population of Oregon in 1970 was 379,000. A total of 63 cases were reported. These tumours and cysts are an uncommon problem.

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The Surgical Management of Sacrococcygeal Teratomas with Intrapelvic Extension

Cited by 39 publications

References 4 publications

Malignant sacrococcygeal teratoma in the adult

Malignant sacrococcygeal teratoma in the adult

Pluripotent stem cells and their niches

Postrectal Neoplasms and Cysts

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