intensity for the sustained achievement of desirable program goals and population outcomes. This understudied area has been identified as one of the most significant translational research problems. Adding to this challenge is uncertainty regarding the extent to which intervention adaptation and evolution are necessary to address the needs of populations that differ from those in which interventions were originally tested or implemented. This review critically examines and discusses conceptual and methodological issues in studying sustainability, summarizes the multilevel factors that have been found to influence the sustainability of interventions in a range of public health and health care settings, and highlights key areas for future research.
AbstractThere is strong interest in implementation science to address the gap between research and practice in public health. Research on the sustainability of evidence-based interventions has been growing rapidly. Sustainability has been defined as the continued use of program components at sufficient (17,97,109). Although numerous evidence-based public health interventions and clinical preventive strategies and treatments are available, it can be challenging to implement and sustain them outside of controlled settings, particularly if they were originally tested in narrow populations or unrepresentative circumstances (49). As a rapidly growing field, implementation science has focused on understanding factors and strategies that influence the initial adoption and integration of evidence-based interventions (EBIs) in real-world settings (103). Whereas significant advancements have been made in understanding the adoption and implementation of EBIs across a range of community and health care settings, less is known about their sustainability. Recently, experts have prioritized sustainability as an understudied area (45), identifying it as "one of the most significant translational research problems of our time" (103, p. 2) and as a persistent challenge across a range of settings and service delivery sectors, and across health behaviors and outcomes.Maximizing the public health impact of EBIs will require investing in sustainability research. This research will enable us to better understand what factors and processes influence the sustainability of interventions and how to plan proactively for the continuation of EBIs. Moreover, there has been growing consideration of the policy and ethical implications of developing effective health programs without investing in sustainability (118). Researchers, health leaders, advocates, policy makers, practitioners, and funders alike have concerns about the long-term impact and value of their investment in discontinued interventions. In addition to lost investments, time, and resources, there are other reasons for which advancing our understanding of the sustainability of EBIs has value (99, 122). Maintaining effective programs and practices is critical for achieving health benefits, particularly if there is a latency period betwee...