The syndrome of posterior thalarnic hemorrhage

Hirose, Genjiro; Kosoegawa, H; Saeki, Mitsuo; Kitagawa, Yoshinobu; Oda, Rokuhei; Kanda, Shigeharu; Matsuhira, Toshimasa

doi:10.1212/wnl.35.7.998

Cited by 32 publications

(10 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The hypometric saccades induced by Vim DBS might be explained by the disruption of the cortex–cerebellum network because the cerebellum is involved in the control of saccade amplitude (Robinson & Fuchs, 2001; see also Brigell et al. , 1984; Hirose et al. , 1985; Gaymard et al.…”

Section: Thalamusmentioning

confidence: 99%

Probing basal ganglia functions by saccade eye movements

Watanabe

Munoz

2011

Eur J of Neuroscience

View full text Add to dashboard Cite

The basal ganglia (BG) are a group of subcortical structures involved in diverse functions, such as motor, cognition and emotion. However, the BG do not control these functions directly, but rather modulate functional processes occurring in structures outside the BG. The BG form multiple functional loops, each of which controls different functions with similar architectures. Accordingly, to understand the modulatory role of the BG, it is strategic to uncover the mechanisms of signal processing within specific functional loops that control simple neural circuits outside the BG, and then extend the knowledge to other BG loops. The saccade control system is one of the best-understood neural circuits in the brain. Furthermore, sophisticated saccade paradigms have been used extensively in clinical research in patients with BG disorders as well as in basic research in behaving monkeys. In this review, we describe recent advances of BG research from the viewpoint of saccade control. Specifically, we account for experimental results from neuroimaging and clinical studies in humans based on the updated knowledge of BG functions derived from neurophysiological experiments in behaving monkeys by taking advantage of homologies in saccade behavior. It has become clear that the traditional BG network model for saccade control is too limited to account for recent evidence emerging from the roles of subcortical nuclei not incorporated in the model. Here, we extend the traditional model and propose a new hypothetical framework to facilitate clinical and basic BG research and dialogue in the future.

show abstract

Section: Thalamusmentioning

confidence: 99%

Probing basal ganglia functions by saccade eye movements

Watanabe

Munoz

2011

Eur J of Neuroscience

View full text Add to dashboard Cite

show abstract

“…An oculomotor function for the central and posterolateral thalamus has been suggested by animal studies showing that saccades can be elicited by electrical stimulation of thalamic nuclei [1][2][3] and that single units in them are active in relation to saccades. 4 5 Abnormalities of voluntary and visually triggered saccades have been reported in patients with acute thalamic lesions, [6][7][8][9] most of whom had hemispatial neglect. It is not clear from these reports whether the thalamus has a specific oculomotor function, or whether the deficits reported reflect the role of the thalamus in the control of visual attention.…”

mentioning

confidence: 99%

Effects of lesions of the human posterior thalamus on ocular fixation during voluntary and visually triggered saccades

Rafal

2004

Journal of Neurology, Neurosurgery & Psychiatry

View full text Add to dashboard Cite

Objective: To investigate the role of the posterior thalamus in controlling voluntary and visually triggered eye movements and ocular fixation. Methods: The latency to initiate saccades to peripheral targets (visually triggered) and in response to verbal commands (voluntary) was measured in three patients with unilateral lesions of the posterior thalamus, in normal controls, and in neurological controls with Parkinson's disease. On half the trials a fixation point offset simultaneously with target onset, and on half it remained visible. Results: Offset of the fixation point simultaneous with target onset decreased saccade latency for both voluntary and visually triggered eye movements in controls, but only for voluntary saccades in patients with thalamic lesions. Conclusions: These findings suggest that separate neural systems control fixation when making voluntary and visually triggered eye movements, and that the thalamus is involved in the control of fixation for visually triggered but not for voluntary saccades.

show abstract

“…By contrast, aphasia secondary to thalamic injury has rarely been described in children. In Hirose's series of 18 patients under 13-years old with thalamic tumors, one right-handed patient with a left-sided lesion had dysphasia: 'mainly a naming difficulty' (Hirose 1985(Hirose , p 1000. Among 18 patients of all ages undergoing stereotaxic thalamotomy for movement disorders, one teenager was included who developed memory and language disturbances after lesioning of the left ventrolateral thalamus (Rossitch et al 1988).…”

mentioning

confidence: 99%

Acquired aphasia in children after surgical resection of left‐thalamic tumors

Nass¹,

Boyce²,

Leventhal³

et al. 2000

Develop Med Child Neuro

View full text Add to dashboard Cite

Five children (three males, two females; four right‐, one left‐handed; age range 6 to 14 years) who developed aphasia after gross‐total excision of left predominantly thalamic tumors are reported. Three patients had Broca aphasia, one had mixed transcortical aphasia, and one patient had conduction aphasia. In the months after surgery, three children improved while receiving radiation and/or chemotherapy, although none recovered completely. Two patients with malignant tumors developed worsening aphasia when the tumor recurred, and later died. Two of three patients tested had visuospatial difficulties in addition to language deficits. Attention and executive functioning were affected in three of three patients tested. Memory, verbal and/or visual functioning, were affected in four of four patients tested. Both patients who were tested showed transient right hemineglect. Two of two patients tested were probably apraxic. The wide range of deficits in these children highlights the importance of the thalamus and other subcortical structures in developing cognition.

show abstract

The syndrome of posterior thalarnic hemorrhage

Cited by 32 publications

References 0 publications

Probing basal ganglia functions by saccade eye movements

Probing basal ganglia functions by saccade eye movements

Effects of lesions of the human posterior thalamus on ocular fixation during voluntary and visually triggered saccades

Acquired aphasia in children after surgical resection of left‐thalamic tumors

Contact Info

Product

Resources

About