The synergistic enhancement of silver nanocubes and graphene oxide on surface plasmon-coupled emission

“…The SPCE signal is measured in the reverse kretschmann (RK) configuration at a wavelength of 532 nm (Figure 25a). The results obtained showed that the fluorescence intensity of the SPCE structure with AgNCs and GO had a signal intensity thirty times higher than the structures without GO and NCs (Figure 25b) [95]. Xie et al amplified the SPCE signal in gold using GO and applied it to detect human IgG.…”

Section: Graphene-based Plasmon Coupled Emission Biosensormentioning

confidence: 99%

A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects

Nurrohman

Chiu

2021

Nanomaterials

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The surface plasmon resonance (SPR) biosensor has become a powerful analytical tool for investigating biomolecular interactions. There are several methods to excite surface plasmon, such as coupling with prisms, fiber optics, grating, nanoparticles, etc. The challenge in developing this type of biosensor is to increase its sensitivity. In relation to this, graphene is one of the materials that is widely studied because of its unique properties. In several studies, this material has been proven theoretically and experimentally to increase the sensitivity of SPR. This paper discusses the current development of a graphene-based SPR biosensor for various excitation methods. The discussion begins with a discussion regarding the properties of graphene in general and its use in biosensors. Simulation and experimental results of several excitation methods are presented. Furthermore, the discussion regarding the SPR biosensor is expanded by providing a review regarding graphene-based Surface-Enhanced Raman Scattering (SERS) biosensor to provide an overview of the development of materials in the biosensor in the future.

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“…It is known as a strong interaction between the fluorophores in the vicinity of metal films and the surface plasma leading to the highly directional p-polarized and wavelength-resolved emission. [22] SPCE can greatly improve the collection efficiency of nondirectional dipoles, making the collected fluorescence signal up to 50 % of the overall intensity, [20] while the signal of fluorescence in the free space (FSF) collected by conventional detection methods is less than 1 % of the total. [23] Since SPCE only has a coupling enhancement effect on molecules in the near-field range, it has greater advantages in the detection of nano-sized biological macromolecules such as nucleic acids [24,25] and proteins.…”

Section: Introductionmentioning

confidence: 99%

“…Surface plasmon coupled emission (SPCE) technology [18–21] provides new ideas for solving these problems. It is known as a strong interaction between the fluorophores in the vicinity of metal films and the surface plasma leading to the highly directional p‐polarized and wavelength‐resolved emission [22] . SPCE can greatly improve the collection efficiency of non‐directional dipoles, making the collected fluorescence signal up to 50 % of the overall intensity, [20] while the signal of fluorescence in the free space (FSF) collected by conventional detection methods is less than 1 % of the total [23] .…”

Section: Introductionmentioning

confidence: 99%

Surface Plasmon Coupled Directional Emission for Integrated Fluorescence‐Raman Biodetection: A Proof‐of‐Concept Study

et al. 2022

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The development of multi‐functional nanoplatforms has attracted much attention. The realization of fluorescence and Raman dual‐mode bio‐detection typically needs complicated switching procedures or algorithm processes. In this work, we propose that a surface plasmon coupled emission (SPCE) technique could be used to break the bottleneck. Our approach enabled Raman spectra which would normally suffer interfered by strong fluorescence signal to be distinguished, simply by respective measurements at different angles. As a proof of concept, we prepared dual‐mode nano‐composites for measurement. Herein, in SPCE, fluorescence was sharply distributed at 46° and Raman at 50°. Attributed to the unique directional radiation feature, collection efficiency increased dramatically, with nearly 5‐fold and 14‐fold absolute intensity enhancement compared to conventional fluorescence and Raman method. Meanwhile, Raman detectability could be improved dramatically in SPCE detection in contrast to free space measurement in one single wavelength excitation device, for serious fluorescence interference to Raman tags could be eliminated.

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The synergistic enhancement of silver nanocubes and graphene oxide on surface plasmon-coupled emission

Cited by 39 publications

References 35 publications

Plasmonic nanosensors for point-of-care biomarker detection

Plasmonic nanosensors for point-of-care biomarker detection

A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects

Surface Plasmon Coupled Directional Emission for Integrated Fluorescence‐Raman Biodetection: A Proof‐of‐Concept Study

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