The synergistic potential of various teas, herbs and therapeutic drugs in health improvement: a review

Malongane, Florence; McGaw, Lyndy Joy; Mudau, Fhatuwani N.

doi:10.1002/jsfa.8472

Cited by 132 publications

(77 citation statements)

References 105 publications

(173 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Meta-analysis papers need to 'separate out' green and black tea (and indeed emerging tea forms) so their individual effects can be better deciphered. There is evidence that various types of teas could act synergistically which could have health benefits to humans [7]. However, their individual effects first need to be clearly understood before cumulative effects are studied.…”

Section: Discussionmentioning

confidence: 99%

“…Yuan et al [36]; Khalesi S et al [6]; Onakpoya I et al [7]; Kim et al [37]; Zheng et al [38] Green and black tea types when analysed together (Cochrane review) show favourable effects on LDL cholesterol.…”

Section: Health Outcome Strength and Amount Of Evidence From Human Stmentioning

confidence: 99%

“…Yuan et al [36]; Khalesi et al [6]; Onakpoya I et al [7]; Kim et al [37]; Zheng et al [38] Zhao et al [34] Longer-term trials imply that black tea may reduce triglyceride levels, alter body fat distribution and increase fat excretion.…”

Section: Strength and Amount Of Evidence Referencesmentioning

confidence: 99%

“…Common bioactive compounds found in green teas include flavan-3-ols (catechins) (also called flavanols), proanthocyanidins (tannins) and flavonols. Black tea is a good provider of theaflavins and thearubigins whilst herbal teas can contain a diverse range of polyphenols [7].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Effects Of Tea Consumption On Measures Of Cardiovascular Disease: A Systematic Review Of Meta-Analysis Studies And Randomised Controlled Trials

Etheridge¹,

Bond²,

Derbyshire³

2018

J Nutr Food Sci

View full text Add to dashboard Cite

Background: The results of meta-analysis studies and randomised controlled trials (RCTs) published in the last 10 years were collated and the effect of tea consumption on measures of cardiovascular disease (CVD) was considered. Methods: PubMed was systematically searched for relevant meta-analysis papers and RCTs. Inclusion and exclusion of studies, data extraction, and quality assessment were conducted according to the PRISMA statement. The Jadad criteria was applied to decipher the quality of RCTs. Results: Findings from 19 meta-analysis and 23 randomised controlled trials (n=1,422 participants) were evaluated. Clear evidence was found for blood pressure where 4 to 5 cups of black or green tea daily related to risk reduction. Moderate evidence was of a positive effect of green tea and its associated catechins on total and lowdensity lipoprotein (LDL) reduction. Growing evidence indicates that tea drinking could protect vascular health and reduce inflammation. A wider range of tea forms (chamomile tea, goishi tea, hibiscus tea, sour tea, rooibos tea) are increasingly being studied and also appear to have potentially favourable effects on markers of CVD. Conclusion: Tea drinking appears to play a significant role in blood pressure reduction, particularly amongst those with prehypertension or hypertension. Green tea has beneficial effects on total and LDL cholesterol reduction. Tea drinking in general appears to aid vascular function and the reduction of inflammation. Ongoing long-term trials are needed especially in relation to other tea forms alongside black and green tea.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Health Outcome Strength and Amount Of Evidence From Human Stmentioning

confidence: 99%

Section: Strength and Amount Of Evidence Referencesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effects Of Tea Consumption On Measures Of Cardiovascular Disease: A Systematic Review Of Meta-Analysis Studies And Randomised Controlled Trials

Etheridge¹,

Bond²,

Derbyshire³

2018

J Nutr Food Sci

View full text Add to dashboard Cite

show abstract

“…Tea is one of the most popular non-alcoholic beverages in the world today, favored for its unique aroma and taste [1]. Ectropis obliqua Prout (Lepidoptera:Geometridae) is a chewing defoliator in tea plantations, causing devastating effects on the quality, yield, and growth of tea plants [2,3].…”

Section: Introductionmentioning

confidence: 99%

Insecticidal Activity and Insecticidal Mechanism of Total Saponins from Camellia oleifera

et al. 2019

View full text Add to dashboard Cite

Chemical pesticides are commonly used during the cultivation of agricultural products to control pests and diseases. Excessive use of traditional pesticides can cause environmental and human health risks. There are ongoing searches for new plant-derived pesticides to reduce the use of chemical pesticides. In this study, tea saponin extracts of different purities were extracted from Camellia oleifera seeds using AB-8 macroporous resin and gradient elution with ethanol. The insecticidal effects of the tea saponin extracts were evaluated by contact toxicity tests and stomach toxicity tests using the lepidopteran pest of tea plantation, Ectropis obliqua. The total saponins extracted using 70% ethanol showed strong contact toxicity (LC50 = 8.459 mg/L) and stomach toxicity (LC50 = 22.395 mg/L). In-depth mechanistic studies demonstrated that tea saponins can disrupt the waxy layer of the epidermis, causing serious loss of water, and can penetrate the inside of the intestine of E. obliqua. After consumption of the tea saponins, the intestinal villi were shortened and the cavities of the intestinal wall were disrupted, which resulted in larval death. This study highlights the potential of tea saponins as a natural, plant-derived pesticide for the management of plant pests.

show abstract

Eugenol–piperine loaded polyhydroxy butyrate/polyethylene glycol nanocomposite‐induced apoptosis and cell death in nasopharyngeal cancer (C666‐1) cells through the inhibition of the PI3K/AKT/mTOR signaling pathway

Sun

Veeraraghavan

Surapaneni³

et al. 2021

J Biochem & Molecular Tox

View full text Add to dashboard Cite

Nasopharyngeal cancer is a malignancy developing from the nasopharynx epithelium due to smoking and nitrosamine‐containing foods. Nasopharyngeal cancer is highly endemic to Southeast Asia. Eugenol and piperine have shown many anticancer activities on numerous cancer types, like colon, lung, liver, and breast cancer. In this study, we amalgamated eugenol and piperine loaded with a polyhydroxy butyrate/polyethylene glycol nanocomposite (Eu‐Pi/PHB‐PEG‐NC) for better anticancer results against nasopharyngeal cancer (C666‐1) cells. In the current study, nasopharyngeal cancer cell lines C666‐1 were utilized to appraise the cytotoxic potential of Eug‐Pip‐PEG‐NC on cell propagation, programmed cell death, and relocation. Eu‐Pi/PHB‐PEG‐NC inhibits cellular proliferation on C666‐1 cells in a dose‐dependent manner, and when compared with 20 µg/ml, 15 µg/ml of loaded mixture evidently restrained the passage aptitude of C666‐1 cells, this was attended with a downregulated expression of mitochondrial membrane potential. Treatment with 15 µg/ml Eu‐Pi/PHB‐PEG‐NC suggestively amplified cell apoptosis in the C666‐1 cells. Furthermore, its cleaved caspase‐3, 8, and 9 and Bax gene expression was augmented and Bcl‐2 gene expression was diminished after Eu‐Pi/PHB‐PEG‐NC treatment. Additionally, our data established that the collective effect of Eu‐Pi/PHB‐PEG‐NC loaded micelles inhibited the expansion of C666‐1 cells augmented apoptosis connected with the intrusion of PI3K/Akt/mTOR signaling pathway.

show abstract

The synergistic potential of various teas, herbs and therapeutic drugs in health improvement: a review

Cited by 132 publications

References 105 publications

Effects Of Tea Consumption On Measures Of Cardiovascular Disease: A Systematic Review Of Meta-Analysis Studies And Randomised Controlled Trials

Effects Of Tea Consumption On Measures Of Cardiovascular Disease: A Systematic Review Of Meta-Analysis Studies And Randomised Controlled Trials

Insecticidal Activity and Insecticidal Mechanism of Total Saponins from Camellia oleifera

Eugenol–piperine loaded polyhydroxy butyrate/polyethylene glycol nanocomposite‐induced apoptosis and cell death in nasopharyngeal cancer (C666‐1) cells through the inhibition of the PI3K/AKT/mTOR signaling pathway

Contact Info

Product

Resources

About