The synthesis and photophysical properties of novel cationic tetra pyridiloxy substituted aluminium, silicon and titanium phthalocyanines in water

Silicon phthalocyanines: synthesis and resurgent applications

“…One extensive methodology pursued to improve the aqueous solubility is the incorporation of nitrogen rich substituents in the axial or peripheral positions of SiPcs, which can be readily alkylated to give quaternary ammonium salts using methyliodide, dimethyl sulfate or 1,3-propanedisultones to obtain cationic water soluble SiPc derivatives, mostly suitable for biological applications (Scheme 12). 15,17,19,33,59,69,85,86 SiPcs in photodynamic therapy (PDT) of cancer. Photodynamic therapy is a minimally-invasive anticancer modality which typically involves a local or systemic administration of a photosensitizer followed by activation in the cancerous tissues with light irradiation.…”

Phthalocyanines Structure Versus Photodynamic Effectiveness towards Pathogenic Microorganisms: Our Recent Experience

“…It is well accepted that cationic dyes are more likely to taken up by the bacterial and fungal species as a result of the nature of the cell wall and the binding process tend to occur via an electrostatic mechanism of interactions [76,77]. The fluorescence confocal microscopy studies showed that the water-soluble cationic LuPcs have the surface localization in fungal cells with relatively high amount and in biofilms with extension inside the fungal cells.…”

Zinc(II) 2,9,16,23-tetrakis[4-(N-methylpyridyloxy)]-phthalocyanine anchored on an electrospun polysulfone polymer fiber: Application for photosensitized conversion of methyl orange

“…2a, shows some aggregation characteristic of quarternized phthalocyanines in solution [24,28]. Aggregation is undesirable for the generation of singlet oxygen, a key property for any photosensitizing agent.…”