The synthesis of 1,2-azaphospholes, 1,2-azaphosphorines and 1,2-azaphosphepines

Abstract

1,2-Azaphospholes, 1,2-azaphosphorines and 1,2-azaphosphepines are prominent phosphorus heterocycles and are of interest due to their potent pharmacological activities. In this review, we provide the available literature data on the synthesis of 1,2-azaphospholes, 1,2-azaphosphorines and 1,2-azaphosphepines.

An Organocatalyzed Multicomponent Reaction: A Rapid and Efficient Practical Approach for 4H‐pyrano[3,2‐c]quinoline‐3‐carbonitriles Synthesis

“…[49] The leading attention directed towards multi-functionalized quinolinones using 4-hydroxyquinoline-2-one precursor considering useful naturally occur-ring intermediates for several medicinal products [50][51][52] and its biological significance. [53][54][55][56] Additionally, 4-hydroxyquinolin-2(1H)-one scaffolds have antischistosomal, [57] antibacterial, [58] anticancer [59][60][61] and antimicrobial [62] pharmacological activities. Also, it is useful in manufacturing azo dyestuffs as well as dyeing synthetic and natural fibers.…”