The Synthesis of 1H‐Pyrroles

Effects of Imidazole-Type Ligands in CuI/TEMPO-Mediated Aerobic Alcohol Oxidation

“…We attribute this to a weaker electron density donation into the IM ring, leading, in turn, to slower electron transfer from Cu I to O 2 and, consequently, to slower Cu II formation in the first reaction step. The reason for this might be the poor resonance donation of vinyl and phenyl substituents. − …”

The rearrangement of 3-nitropyridinium salts to 3-nitropyrroles

“…3 The rearrangement of 3-amino-2-bromopyridine into 3-cyanopyrrole under the action of potassium amide in liquid ammonia was the first example of the recyclization of a pyridine ring to a pyrrole. The pyrrole ring of 3-cyanopyrrole is formed from an acyclic intermediate formed after breaking pyridine ring С2-С3 bond.…”

Copper-Catalyzed Three-Component Reactions of α-Ketoaldehyde, 1,3-Dicarbonyl Compound, and Organic Boronic Acid in Water: A Route to 1,4-Diketones

“…1,4-Dicarbonyl compounds are prominent building blocks to prepare a broad range of carbocyclic and heteroaromatic compounds in organic synthesis. They have been regarded as highly versatile synthons for the synthesis of appealing valuable molecules, such as furan, thiophene, pyrrole, and pyridazines derivatives. Although 1,4-dicarbonyl compounds have been found in a wide range of applications in the chemical and pharmaceutical fields, the green and efficient synthesis of them remains a significant challenge .…”