The Synthesis of 1‐Phenyl‐|4,5|‐Decanes

Abstract

Marc Van P a r y s a n d M a u r i t s V a n d e w a l l e x D e p a r t m e n t o f O r g a n i c C h e m i s t r y , S t a t e U n i v e r s i t y o f Ghent L a b o r a t o r y f o r O r q a n i c S y n t h e s i s , K r i j g s l a a n , 271 ( S . 4 ) , B-9000 GENT ( B e l g i u m ) TWO r o u t e s s t a r t i n g from 1-benzyl-4-0x0-piperidine h a v e b e e n e x p l o r e d . The t i t l e compounds a r e i s o s t e r i c t o t h e 1,3,8-triazaspirol4,5ldecane s t r u c t u r e p r e s e n t i n i m p o r t a n t n e u r o l e p t i c a q e n t s .