The synthesis of isoxazolines and dihydrooxazines by Pd-catalyzed oxyalkynylation alkenyl oximes with alkynyl bromides

Abstract

Synthesis of isoxazolines and dihydrooxazines bearing an alkyne group by Pd-catalyzed oxyalkynylation of alkenyl oximes with alkynyl bromides. This new approach has a broad substrate scope and good functional tolerance.