The synthesis of some 3-amino-2-halomethyl-, 2-halomethyl-3-(subst.amino)- and 2-halomethyl-3-hetarylquinazolin-4(3)-ones as potential plant protecting agents

Synthesis and Antimicrobial Activities of Some New Thieno and Furopyrimidine Derivatives

“…Further more, many condensed heterocyclic systems, especially when linked to a pyrimidine ring as thienopyrimidine play an important role as potent analgesic [1], anti-inflammatory [1][2][3][4][5], antipyretic [6][7][8], antimicrobial [9][10], anticonvulsant [11], fungicidal [12], antiplatelet activities [13][14][15], and other central nervous system (CNS) affecting activities [16]. In addition, pyrimidine nucleus can be found in a broad variety of antibacterial, anticancer and anti-tumor agents as well as in agrochemicals and veterinary products [17][18].…”

Synthesis of 3‐aminoalkyl‐2‐arylaminoquiazolin‐4(3H)‐ones and 3,3′‐disubstituted bis‐2‐arylaminoquinazolin‐4(3H)‐ones via reactions of 1‐aryl‐3‐(2‐ethoxycarbonylphenyl)carbodiimides with diamines

“…This is due, in part, to the broad spectrum of their biological properties. Some of these activities include antimicrobial [5,6], anti-inflammatory [7,8], antifungal [9], anticancer [10], antidiabetic [11], anticonvulsant [12], analgesic [13], antibacterial [14], protein tyrosine kinase inhibitors [15], EGFR inhibitors [16], PDGFR phosphorylation inhibitors [17], CNS depressants [18], antitumor activity [19] and AMPA receptor-antagonistic properties [20,21]. Furthermore, the heterocyclic core constitutes more than 40 alkaloids [22] isolated from natural products, and some show interesting biological profiles such as antimalarial [23] and diuretic [24] properties.…”

Green and high efficient synthesis of triaza‐benzo[b]fluoren‐6‐one derivatives in water under microwave irradiation

“…Varied biological activities have been attributed to triaza-benzo [b]fluoren-6-one compounds, including analgesic, antiinflamatory, antipyretic [6][7][8], antimicrobial [9], anticonvulsant [10], fungicidal [11], antidepressant or other central nervous system affecting activities [12], and recently two original triaza-benzo [b]fluoren-6-one compounds were described as a new class of potent antitumour compounds [13].…”