2023
DOI: 10.2147/jir.s385308
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The Systemic Inflammation Score is Associated with the Survival of Patients with Prostate Cancer

Abstract: Background:The systemic inflammation score (SIS) based on the albumin (Alb) level and lymphocyte-to-monocyte ratio (LMR), has been associated with survival in some cancers. However, its prognostic role in prostate cancer (PCa) remains unclear. Methods: The associations between the SIS and the clinicopathological features of PCa were evaluated. The correlations between the SIS and overall survival (OS) and progression-free survival (PFS) were assessed using Kaplan-Meier analysis and the Log rank test. Univariat… Show more

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Cited by 4 publications
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“… 6 Current research primarily explores the impact of local chronic inflammation, such as prostatitis, on the risk of developing PCa. 7 Although existing epidemiological evidence indicates a strong association between systemic inflammation and unfavorable prognosis in PCa patients, 8 the link between systemic inflammation and PCa risk is poorly defined. Given the close association of inflammation with PCa, further investigating the PCa risk using systemic inflammatory markers across adults without a PCa history is of great significance.…”
Section: Introductionmentioning
confidence: 99%
“… 6 Current research primarily explores the impact of local chronic inflammation, such as prostatitis, on the risk of developing PCa. 7 Although existing epidemiological evidence indicates a strong association between systemic inflammation and unfavorable prognosis in PCa patients, 8 the link between systemic inflammation and PCa risk is poorly defined. Given the close association of inflammation with PCa, further investigating the PCa risk using systemic inflammatory markers across adults without a PCa history is of great significance.…”
Section: Introductionmentioning
confidence: 99%