2009
DOI: 10.1016/j.jhep.2009.04.017
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The systemic inflammatory response syndrome in cirrhotic patients: Relationship with their in-hospital outcome

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Cited by 208 publications
(165 citation statements)
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“…Hence, both the circulatory and immune dysfunction are responsible for renal injury in these patients. This has been demonstrated by various studies in the past [58,[81][82][83][84][85][86].…”
Section: Renal Failurementioning
confidence: 66%
“…Hence, both the circulatory and immune dysfunction are responsible for renal injury in these patients. This has been demonstrated by various studies in the past [58,[81][82][83][84][85][86].…”
Section: Renal Failurementioning
confidence: 66%
“…With reference to outcome in liver cirrhosis, Cazzaniga and coworkers have reported that the systemic inflammatory response syndrome (SIRS) is closely related to severity of liver disease in cirrhotic patients as evidenced in the relationship with serum bilirubin, INR and the Model for End-Stage Liver Disease (MELD) score [33]. In their study, SIRS also predicted the development of portal hypertension-related complications and was closely correlated with in-hospital death.…”
Section: Discussionmentioning
confidence: 98%
“…This syndrome correlates with bacterial infection at admission and has been shown to be associated with a poor outcome. [7] Animal studies have identified the gut as the principal source of infection in liver cirrhosis, mainly through bacterial overgrowth and translocation in the small bowel. However, cultures of small intestinal mucosal bacteria in cirrhotic patients have shown that these microbiota are qualitatively and quantitatively normal.…”
Section: Sepsis In Liver Cirrhosismentioning
confidence: 99%