The TandemHeart®, percutaneous transseptal left ventricular assist device: a safeguard in high-risk percutaneous coronary interventions. The six-year Rotterdam experience

Vranckx, Pascal; Meliga, Emanuele; Jaegere, Peter P.T. de; Ent, Martin van den; Regar, Evelyn; Serruys, Patrick W.

doi:10.4244/eijv4i3a60

Cited by 51 publications

(21 citation statements)

References 18 publications

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“…These results, against the background of preserved periprocedural hemodynamics in this patient series, supports the hypothesis that TH support allows for a safe and optimal treatment technique. As opposed to other modalities of percutaneous cardiopulmonary support (CPS) used in this indication, [15,16] the TandemHeart system keeps the patient's lungs as its own ventilator and may be used to support patients for a longer period of time without major haematological or pulmonary complications (up to 10 days in our experience) [7]. In our series, only two patients required general anaesthesia, the device was well tolerated.…”

Section: Discussionmentioning

confidence: 86%

“…The median (range) calculated logistic EuroScore was 13.64 (7.46-29.67). The median (range) risk of mortality and morbidity or mortality calculated by the Mayo clinical risk score was 7 [6][7][8]. The median (range) syntax score was 43 (41-50).…”

Section: Baseline and Procedural Characteristicsmentioning

confidence: 99%

“…This system allows for rapid implementation of circulatory support, delivering up to 4.5 L of blood flow per minute, using standard interventional techniques in the catheterization laboratory [6,7].…”

Section: Introductionmentioning

confidence: 99%

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Assisted circulation using the TandemHeart® during very high‐risk PCI of the unprotected left main coronary artery in patients declined for CABG

Vranckx

Schultz

Valgimigli

et al. 2009

Cathet Cardio Intervent

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Section: Discussionmentioning

confidence: 86%

Section: Baseline and Procedural Characteristicsmentioning

confidence: 99%

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Assisted circulation using the TandemHeart® during very high‐risk PCI of the unprotected left main coronary artery in patients declined for CABG

Vranckx

Schultz

Valgimigli

et al. 2009

Cathet Cardio Intervent

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“…Experience of elective implantation of TandemHeart ahead of high-risk PCI has been reported in several observational studies [40] [41] [42] [43]. These studies, although small, confirm that TandemHeart is technically feasible and may provide excellent hemodynamic support.…”

Section: Tandemheart In High-risk Pcimentioning

confidence: 58%

Use of Left Ventricular Support Devices During Acute Coronary Syndrome and Percutaneous Coronary Intervention

Spiro

Doshi

2014

Curr Cardiol Rep

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In an effort to improve outcomes in percutaneous coronary intervention (PCI), percutaneous ventricular assist devices (PVADs) have been investigated in (1) high-risk PCI, (2) acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) and (3) in AMI without CS. PCI has become an increasing complex due to an ageing population with complex disease and the frequent presence of impaired LV function. Patients undergoing high-risk PCI in these circumstances are prone to acute cardiovascular collapse. Additionally, mortality in AMI complicated by CS remains high. Lastly, LV support during AMI may reduce infarct size and therefore preserve LV function. At present, four commercially available devices exist: intra-aortic balloon pump counterpulsation (IABP), Impella, TandemHeart and extracorporeal membrane oxygenation (ECMO). These devices are employed in an effort to increase cardiac output, mean arterial pressure (MAP) and coronary perfusion and to reduce pulmonary capillary wedge pressure (PCWP). The mechanism of action differs with each device, and there are advantages and disadvantages. In this update, we discuss recent data describing the use of PVADs to support patients with AMI with or without cardiogenic shock and during high-risk PCI. We focus on the unique features of each device, highlighting strengths, weaknesses and frequently encountered complications, which may be important when tailoring the most appropriate PVAD therapy to an individual patient's need.

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“…Two somewhat larger case series have been published recently. 60,61 The first evaluated the TandemHeart in 23 patients undergoing high-risk PCI. Implantation was successful in all patients, with PCI successful in 91%, although 5 patients died with the device in place, primarily because of preexistent cardiogenic shock.…”

Section: Tandemheartmentioning

confidence: 99%

Novel Percutaneous Cardiac Assist Devices

Naidu

2011

Circulation

120

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The TandemHeart®, percutaneous transseptal left ventricular assist device: a safeguard in high-risk percutaneous coronary interventions. The six-year Rotterdam experience

Cited by 51 publications

References 18 publications

Assisted circulation using the TandemHeart® during very high‐risk PCI of the unprotected left main coronary artery in patients declined for CABG

Assisted circulation using the TandemHeart® during very high‐risk PCI of the unprotected left main coronary artery in patients declined for CABG

Use of Left Ventricular Support Devices During Acute Coronary Syndrome and Percutaneous Coronary Intervention

Novel Percutaneous Cardiac Assist Devices

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