The tear, flare, and repair model of osteoarthritis

Birrell, Fraser; Johnson, Ann

doi:10.1136/bmj.o1028

BMJ

2022

DOI: 10.1136/bmj.o1028

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The tear, flare, and repair model of osteoarthritis

Fraser Birrell

Ann Johnson

Abstract: Lessons from the Hip Injection Trial (HIT)

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2024

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Cited by 4 publications

(2 citation statements)

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“…If you made these choices, how could professionals and the public be confident that you will take full advantage of the opportunity of a data-centric health service, including a full and frank conversation about companies’ use of health data (doi:10.1136/bmj.o1018)?13 Could you be trusted with striking new evidence that joint injections for osteoarthritis are potentially beneficial and help us rethink osteoarthritis as a disease of tear, flare, and repair instead of wear and tear (doi:10.1136/bmj-2021-068446, doi:10.1136/bmj.o1028)?1415 Or be relied on to learn the lessons from a multinational study of outcomes after revascularisation for acute myocardial infarction (doi:10.1136/bmj-2021-069164)?16 And you would probably struggle to maximise the clear potential of telemedicine for surgery, a potential that is being realised in the international support for the surgeons and people of Ukraine (doi:10.1136/bmj.o1078). 17…”

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confidence: 99%

Choices that fail health and wellbeing

Abbasi¹

2022

BMJ

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mentioning

confidence: 99%

Choices that fail health and wellbeing

Abbasi¹

2022

BMJ

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“…been made to date to mitigate, prevent, or reverse this condition successfully, and safely, despite decades of research [4][5][6][7].…”

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confidence: 99%

Osteoarthritis and Neuromuscular Deficits: Can a Causative Role be Discounted- Key 2017-2022 Observations

Marks

2022

JARH

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Background The origin of osteoarthritis, the most common disabling disorder of older adults remains uncertain. Aim This mini review examines the possible role played by various neuromuscular deficits in the osteoarthritis etiopathogenic process. Methods and Procedures Articles that haveaddressed the current topic of interest and were located in the PUBMED,Google Scholar, and Web of Science electronic data bases as of 2017-2022 were carefully sought and examined. Results Various neuromuscular mechanisms may have a bearing on the development and progression of osteoarthritis, but the data are largely unrelated and observational in nature. Conclusion More research to examine this issue is sorely needed and could have considerable merit in light of the growing populations of older adults at risk for disabling osteoarthritis in the face of few intervention options to help them to achieve an optimal functional level.

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Physiotherapists' Experiences and Perceived Acceptability of Delivering a Knee Bracing Intervention for People With Symptomatic Knee Osteoarthritis in a Randomised Trial (PROP OA): A Qualitative Study

Bullock,

Holden,

Jinks

et al. 2024

Musculoskeletal Care

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ObjectivesTo explore physiotherapists' experiences and perceived acceptability of delivering a bracing intervention for knee osteoarthritis (OA) in the ‘PROvision of braces for Patients with knee OA’ (PROP OA) randomised controlled trial.MethodSemi‐structured telephone interviews with consenting physiotherapists who received the PROP OA training programme and delivered the knee bracing intervention (advice, information and exercise instruction plus knee brace matched to patients' clinical and radiographic presentation and with adherence support). Interviews were recorded and transcribed verbatim. Two‐stage analytic framework: inductive thematic analysis preceded mapping to constructs of the Theoretical Framework of Acceptability.ResultsEight physiotherapists were interviewed and six key themes were developed. Perceptions of the training programme were generally positive, but additional formal training and experiential learning consolidated confidence and skills in novel intervention components. Advice, information, and exercise instruction reflected usual physiotherapy care for knee OA. Physiotherapists were confident in delivering the knee brace, but determining the pattern of knee OA to inform brace type selection was challenging. Physiotherapists valued brace adherence enhancing strategies and the follow‐up appointment to facilitate adherence. Perceived impact of the bracing intervention for people with OA was positive. The bracing intervention was perceived as acceptable, although improving self‐efficacy to deliver novel intervention components (e.g., reading x‐rays) would enhance acceptability.ConclusionThe complex knee bracing intervention was broadly perceived as acceptable by physiotherapists. If implemented within clinical practice beyond the trial, physiotherapists might benefit from not only initial training in brace selection but also ongoing support and mentoring to increase self‐efficacy in delivery.

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The tear, flare, and repair model of osteoarthritis

Abstract: Lessons from the Hip Injection Trial (HIT)

Cited by 4 publications

References 7 publications

Choices that fail health and wellbeing

Choices that fail health and wellbeing

Osteoarthritis and Neuromuscular Deficits: Can a Causative Role be Discounted- Key 2017-2022 Observations

Physiotherapists' Experiences and Perceived Acceptability of Delivering a Knee Bracing Intervention for People With Symptomatic Knee Osteoarthritis in a Randomised Trial (PROP OA): A Qualitative Study

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