“…Furthermore, Silberg & Bulik (2005) demonstrated that comorbidity between eating disorders, anxiety disorders and depressive symptoms is accounted for by shared genetic factors, and with the personality trait "harm avoidance" as a possible pathway. Harm avoidance has been shown to be elevated in individuals with anxiety (Kennedy, Schwab, & Hyde, 2001), depression (Grucza, Przybeck, Spitznagel, & Cloninger, 2003;Kennedy et al, 2001;Marijnissen, Tuinier, Sijben, & Verhoeven, 2002) and eating disorders (Bulik, Sullivan, Carter, & Joyce, 1995;Bulik, Sullivan, Weltzin, & Kaye, 1995;Klump et al, 2000). Moreover, activation of a common biological pathway that influences anxiety, depression, and eating (e.g., the serotonergic system) may also be plausible as such activity has been consistently shown to be abnormal in women with anorexia and bulimia nervosa both during the acute phase of the illness and after recovery (Kaye, 1997a,b;O'Dwyer, Lucey, & Russell, 1996;Wolfe, Metzger, & Jimerson, 1997).…”