2002
DOI: 10.1016/s0165-0327(01)00364-0
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The temperament and character inventory in major depression

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Cited by 76 publications
(49 citation statements)
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“…Consistent with our results, several previous studies have shown higher scores on HA and lower scores on SD and C in patients with UP (Farmer et al, 2003;Hansenne et al, 1999) or in those with BP (Engstrom et al, 2004;Evans et al, 2005) compared to healthy controls. Higher NS (Evans et al, 2005;Nowakowska et al, 2005) and ST (Evans et al, 2005;Loftus et al, 2008;Nowakowska et al, 2005) have also been reported in BP patients compared to controls, though most studies comparing UP patients and controls have shown no significant difference in these two dimensions (Celikel et al, 2009;Evans et al, 2005;Farmer et al, 2003;Hansenne et al, 1999;Kimura et al, 2000;Marijnissen et al, 2002;Nowakowska et al, 2005;Smith et al, 2005). Although the comparison between BPII and UP patients showed similar trends in both genders (i.e., higher NS and ST in BPII), statistical significance between these two disorders was reached only in females.…”
Section: Discussionmentioning
confidence: 91%
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“…Consistent with our results, several previous studies have shown higher scores on HA and lower scores on SD and C in patients with UP (Farmer et al, 2003;Hansenne et al, 1999) or in those with BP (Engstrom et al, 2004;Evans et al, 2005) compared to healthy controls. Higher NS (Evans et al, 2005;Nowakowska et al, 2005) and ST (Evans et al, 2005;Loftus et al, 2008;Nowakowska et al, 2005) have also been reported in BP patients compared to controls, though most studies comparing UP patients and controls have shown no significant difference in these two dimensions (Celikel et al, 2009;Evans et al, 2005;Farmer et al, 2003;Hansenne et al, 1999;Kimura et al, 2000;Marijnissen et al, 2002;Nowakowska et al, 2005;Smith et al, 2005). Although the comparison between BPII and UP patients showed similar trends in both genders (i.e., higher NS and ST in BPII), statistical significance between these two disorders was reached only in females.…”
Section: Discussionmentioning
confidence: 91%
“…TCI is a 240 item true/false questionnaire measuring four dimensions of temperament (novelty seeking (NS), harm avoidance (HA), reward dependence (RD), and persistence (P)) and three dimensions of character (self-directedness (SD), cooperativeness (C), and self-transcendence (ST)), developed on the basis of a psychobiological model of personality. Although TCI has been frequently used in the studies of mood disorders Celikel et al, 2009;de Winter et al, 2007;Engstrom et al, 2004;Farmer et al, 2003;Hansenne et al, 1999;Hirano et al, 2002;Kimura et al, 2000;Loftus et al, 2008;Marijnissen et al, 2002;Matsudaira and Kitamura, 2006;Naito et al, 2000;Richter et al, 2000;, no studies to date have compared TCI score profiles of patients with unipolar and bipolar depression during their depressed states. We aimed to identify personality profiles specific to either unipolar or bipolar depression, which could aid in the were also assessed with the Structured Clinical Interview for DSM-IV by a trained psychiatrist to confirm the diagnosis.…”
Section: Introductionmentioning
confidence: 99%
“…First, the TCI provides personality measures that quantify individual differences in vulnerability to many Axis I disorders (e.g., major depressive disorder, anxiety disorders, eating disorders, substance dependencies, and also psychoses). Indeed, several studies have demonstrated that depressed patients, even in remission states, have higher HA scores and that severity of depression correlates with HA (Corruble, Duret, Pélissolo, Falissard, & Guelfi, 2002;Grucza, Przybeck, Spitznagel, & Cloninger, 2003;Marijnissen, Tuinier, Sijben, & Verhoeven, 2002). Moreover, patients who fail to respond to antidepressant treatments generally have higher HA scores before treatment than the others.…”
mentioning
confidence: 99%
“…Furthermore, Silberg & Bulik (2005) demonstrated that comorbidity between eating disorders, anxiety disorders and depressive symptoms is accounted for by shared genetic factors, and with the personality trait "harm avoidance" as a possible pathway. Harm avoidance has been shown to be elevated in individuals with anxiety (Kennedy, Schwab, & Hyde, 2001), depression (Grucza, Przybeck, Spitznagel, & Cloninger, 2003;Kennedy et al, 2001;Marijnissen, Tuinier, Sijben, & Verhoeven, 2002) and eating disorders (Bulik, Sullivan, Carter, & Joyce, 1995;Bulik, Sullivan, Weltzin, & Kaye, 1995;Klump et al, 2000). Moreover, activation of a common biological pathway that influences anxiety, depression, and eating (e.g., the serotonergic system) may also be plausible as such activity has been consistently shown to be abnormal in women with anorexia and bulimia nervosa both during the acute phase of the illness and after recovery (Kaye, 1997a,b;O'Dwyer, Lucey, & Russell, 1996;Wolfe, Metzger, & Jimerson, 1997).…”
Section: Possible Shared Aetiological Mechanismsmentioning
confidence: 99%