The “Test Your Memory” test performs better than the MMSE in a population without known cognitive dysfunction

Koekkoek, Paula S.; Rutten, Guy E.H.M.; Berg, Esther van den; Sonsbeek, Sanne van; Gorter, Kees J.; Kappelle, L. Jaap; Biessels, Geert Jan

doi:10.1016/j.jns.2013.02.028

Cited by 24 publications

(17 citation statements)

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“…Therefore, a more sensitive, while still clinically meaningful, cognitive Z -score threshold of >1 SD below the mean was chosen. The use of >1 SD below the mean has also been used in older adults with comparatively unimpaired cognition44 and adults with neuropsychiatric conditions,45 as well as in a cerebrovascular disease sample 46…”

Section: Methodsmentioning

confidence: 99%

Serum low-density lipoprotein levels, statin use, and cognition in patients with coronary artery disease

Rej¹,

Saleem

Herrmann

et al. 2016

NDT

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AimStatins have been associated with decreased cognition due to the effects of low concentrations of low-density lipoprotein (LDL) on brain function. This has remained controversial and is particularly relevant to patients with coronary artery disease (CAD), who have an increased risk of cognitive decline and are frequently prescribed statins. This study hypothesized that low concentration of LDL is associated with poor cognition in CAD patients using statins. It also explored the association between high-dose versus low-dose statins on cognition in this population.Patients and methodsBaseline cross-sectional data from a longitudinal study of 120 statin-using CAD patients were examined (mean statin duration 25±43 months). The main outcomes were measures of global cognition and cognitive domains, with poor cognition defined as cognitive performance ≤1 standard deviation below the population age and education adjusted means. A battery of cognitive tests was used to assess verbal memory, executive function, speed of processing, visuospatial memory, and global cognition. Adjusting for age, sex, education, and other covariates, multivariable logistic regression analyses assessed associations between low LDL levels (<1.5 mmol/L), statin use, and poor cognition.ResultsLDL levels were not associated with global cognition or individual cognitive domains. High-dose statin use was associated with higher visuospatial memory (odds ratio, OR [95% confidence interval, CI] =0.12 [0.02–0.66], P=0.01) and executive functioning (OR =0.25 [0.06–0.99], P=0.05). This effect was independent of covariates such as LDL levels.ConclusionLow LDL levels do not appear to be associated with poor cognition in CAD patients using statins. Whether high-dose statin use may have positive effects on cognition in CAD patients could be investigated in future studies.

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Section: Methodsmentioning

confidence: 99%

Serum low-density lipoprotein levels, statin use, and cognition in patients with coronary artery disease

Rej¹,

Saleem

Herrmann

et al. 2016

NDT

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“…Postal surveys were used for practicality and to increase the likelihood of participation. The self-administered TYM screening test correlates significantly better than the Mini-Mental State Examination in detecting cognitive impairment (R 2 =0.78 vs 0.55) when compared with a full cognitive battery 9. It is also validated for use in non-hospital settings 9 10.…”

Section: Methodsmentioning

confidence: 99%

“…The self-administered TYM screening test correlates significantly better than the Mini-Mental State Examination in detecting cognitive impairment (R 2 =0.78 vs 0.55) when compared with a full cognitive battery 9. It is also validated for use in non-hospital settings 9 10. The questionnaire is self-administered in order to remove assessor bias and is therefore useful in postal surveys 11…”

Section: Methodsmentioning

confidence: 99%

Heading in football, long-term cognitive decline and dementia: evidence from screening retired professional footballers

2013

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“…The past four decades have seen growing interest in developing easy-to-administer cognitive screening tools with clinical utility for primary and secondary care settings (Larner, 2013;Zygouris and Tsolaki, 2014). One of the most promising tools is the Test Your Memory (TYM) cognitive test (Brown et al, 2009), which has sound psychometric properties (Brown et al, 2009;Hancock and Larner, 2011), remarkable cross-cultural validity (Hanyu et al, 2011;Abd-Al-Atty et al, 2012;Szczesniak et al, 2013;Ferrero-Arias and Turrion-Rojo, 2014;Iatraki et al, 2014;Muñoz-Neira et al, 2014;Postel-Vinay et al, 2014) and good concurrent validity with established tests, such as the Mini-mental state examination, and the Addenbrooke's cognitive examination test battery (Brown et al, 2009;van Schalkwyk et al, 2012;Koekkoek et al, 2013). However, studies using the TYM were conducted among small clinical samples and did not report on the sociodemographic and cardiometabolic correlates of TYM-defined cognitive groups.…”

Section: Introductionmentioning

confidence: 99%

The Test Your Memory cognitive screening tool: sociodemographic and cardiometabolic risk correlates in a population‐based study of older British men

Papachristou¹,

Ramsay²,

Papacosta³

et al. 2015

Int J Geriat Psychiatry

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ObjectiveThis study aimed to examine the association of Test Your Memory (TYM)‐defined cognitive impairment groups with known sociodemographic and cardiometabolic correlates of cognitive impairment in a population‐based study of older adults.MethodsParticipants were members of the British Regional Heart Study, a cohort across 24 British towns initiated in 1978–1980. Data stemmed from 1570 British men examined in 2010–2012, aged 71–92 years. Sociodemographic and cardiometabolic factors were compared between participants defined as having TYM scores in the normal cognitive ageing, mild cognitive impairment (MCI) and severe cognitive impairment (SCI) groups, defined as ≥46 (45 if ≥80 years of age), ≥33 and <33, respectively.ResultsAmong 1570 men, 636 (41%) were classified in the MCI and 133 (8%) in the SCI groups. Compared with participants in the normal cognitive ageing category, individuals with SCI were characterized primarily by lower socio‐economic position (odds ratio (OR) = 6.15, 95% confidence interval (CI) 4.00–9.46), slower average walking speed (OR = 3.36, 95% CI 2.21–5.10), mobility problems (OR = 4.61, 95% CI 3.04–6.97), poorer self‐reported overall health (OR = 2.63, 95% CI 1.79–3.87), obesity (OR = 2.59, 95% CI 1.72–3.91) and impaired lung function (OR = 2.25, 95% CI 1.47–3.45). A similar albeit slightly weaker pattern was observed for participants with MCI.ConclusionSociodemographic and lifestyle factors as well as adiposity measures, lung function and poor overall health are associated with cognitive impairments in late life. The correlates of cognitive abilities in the MCI and SCI groups, as defined by the TYM, resemble the risk profile for MCI and Alzheimer's disease outlined in current epidemiological models. © 2016 The Authors. International Journal of Geriatric Psychiatry Published by John Wiley & Sons, Ltd.

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The “Test Your Memory” test performs better than the MMSE in a population without known cognitive dysfunction

Abstract: The TYM showed good correlation with a neuropsychological assessment, performed better in discriminating between variations of cognition and showed more agreement with a neuropsychological assessment than the MMSE.

Cited by 24 publications

References 29 publications

Serum low-density lipoprotein levels, statin use, and cognition in patients with coronary artery disease

Serum low-density lipoprotein levels, statin use, and cognition in patients with coronary artery disease

Heading in football, long-term cognitive decline and dementia: evidence from screening retired professional footballers

The Test Your Memory cognitive screening tool: sociodemographic and cardiometabolic risk correlates in a population‐based study of older British men

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