The therapeutic dilemma in pre-transplant asymptomatic aspergilloma: A case report and review of literature

Jha, Vijoy Kumar; Mahapatra, Debasish; Ghana, Parthasarathi; Jairam, Anantharam; Sharma, Pragya

doi:10.4103/1319-2442.335473

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“…An asymptomatic aspergilloma diagnosed during the pre-operative period was resected surgically before RT. The patient was maintained on an optimum balance between immunosuppressive therapy and antifungal prophylaxis [ 45 ]. Similarly, pulmonary mucormycosis which has nearly 100% mortality in RT patients, was managed with surgical resection and antifungals in the perioperative period; this along with decreased immunosuppression post-RT lead to a favorable outcome of RT in ten Indian patients [ 46 ].…”

Section: Ifi In Sot: India Vs the Worldmentioning

confidence: 99%

Epidemiology of Invasive Fungal Infections in Solid Organ Transplant Recipients: an Indian Perspective

Sharma

Rudramurthy

Chakrabarti³

2022

Curr Fungal Infect Rep

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Purpose of Review This review summarizes the available Indian data on epidemiology of invasive fungal infections (IFI) in recipients of solid organ transplants (SOT). The epidemiology is further compared with studies from other parts of the world for each SOT type. Recent Findings The available studies on Indian epidemiology of IFI in SOT are scarce, though the number of SOTs performed in India have increased tremendously in recent years. The limited data from India present a distinct spectrum of infection in transplant recipients with high incidence of mucormycosis. During COVID-19 outbreak, IFI rate increased and renal transplant recipients acquired mucormycosis earlier than previous studies. Summary Maximum data on IFI was available from renal transplant recipients, wherein mucormycosis was the predominant IFI in Indian patients in contrast to invasive candidiasis in majority countries. The other IFIs had varied spectrum. With the increasing number of SOTs being performed and the already persisting high burden of IFI in India, there is an urgent need of larger prospective studies on epidemiology of IFI in transplant recipients.

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Section: Ifi In Sot: India Vs the Worldmentioning

confidence: 99%