The therapeutic possibilities of carboxytherapy for psoriasis

Дроговоз, С. М.; Кононенко, А. Г.; Shchоkina, К. H.; Belik, Galina; Shtroblya, A. L.

doi:10.24959/ubphj.18.192

Cited by 3 publications

(4 citation statements)

References 5 publications

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“…Psoriasis is a common, chronic inflammatory skin disorder affecting about 125 million people worldwide with global variation in the prevalence rate 38 . It appears that carboxytherapy is effective in the management of psoriasis through anti‐inflammatory, antioxidant, antimicrobial, antihypertrophic, reparative, and analgesic properties, tissue detoxification, improvement of immunity status, improvement of tissue trophism, and elimination of venous‐interstitial lymphatic stagnation 39 …”

Section: Indicationsmentioning

confidence: 99%

“…38 It appears that carboxytherapy is effective in the management of psoriasis through anti-inflammatory, antioxidant, antimicrobial, antihypertrophic, reparative, and analgesic properties, tissue detoxification, improvement of immunity status, improvement of tissue trophism, and elimination of venous-interstitial lymphatic stagnation. 39 In a pilot study by Kamel and Abdelghani assessing the efficacy of carboxytherapy in treating psoriasis, 30 patients with chronic localized plaque psoriasis were recruited. Treatment was performed once a week for eight sessions and the subjects were assessed 2 weeks after the last session based on clinical and histopathological criteria.…”

Section: Psoriasismentioning

confidence: 99%

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An overview of the role of carboxytherapy in dermatology

Bagherani

Smoller

Tavoosidana

et al. 2023

J of Cosmetic Dermatology

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BackgroundCarboxytherapy is defined as intradermal and/or subcutaneous microinjections of sterile purified carbon dioxide into different parts of the body for therapeutic aims. The vasodilatation effect and intradermal collagen reorganization associated with carboxytherapy have advantages for aesthetic dermatology and cosmetology.ObjectiveIn the current article, we have reviewed some of the most important indications of this modality in dermatology and aesthetic dermatology.MethodOur review is a narrative one which has gathered some of the most important indications of carboxytherapy in dermatology and cosmetology.ResultsCarboxytherapy has successfully been applied for some dermatologic and cosmetic conditions among which skin aging, cellulite, localized fat deposits, striae distensae, infraorbital hyperpigmentation, scar, lymphedema, androgenetic alopecia, alopecia areata, psoriasis, morphea, and vitiligo are the most important.ConclusionCarboxytherapy can be considered as a safe, minimally‐invasive modality used for rejuvenation, restoration, and recondition of the skin.

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Section: Indicationsmentioning

confidence: 99%

Section: Psoriasismentioning

confidence: 99%

An overview of the role of carboxytherapy in dermatology

Bagherani

Smoller

Tavoosidana

et al. 2023

J of Cosmetic Dermatology

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“…Це внутрішньоклітинний фермент. Тому реакція гідратації з високою швидкістю здійснюється в еритроцитах після того, як СO 2 дифундує туди з плазми крові [18].…”

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“…Але однобічна дифузія аніонів бікарбонату порушила б умови електричної нейтральності, оскільки позитивно заряджені іони К і Na не здатні дифундувати з еритроцитів у плазму. У результаті такого обміну HСО 3 і С1 -, значна частина іонів бікарбонату, що утворилися усередині еритроцитів, дифундує в плазму, тобто тим самим підвищується роль плазми в транспорті вуглекислоти [18].…”

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Interaction of Myoglobin Model with Ligands of Gas Exchange

Zavhorodnia

Коваленко

Minaev

2019

BCUB

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Газообмін для живих організмів-дуже важливий біохімічний процес. При дослідженні різних показників серцево-судинної та дихальної систем постало питання конкуренції різних газів за зв'язування з Fe 2+ гема гемоглобіну. До цього часу ніхто не розглядав можливість зв'язування СО 2 із залізом гемоглобіну. Вперше нами прийнята спроба розглянути цей зв'язок. Розрахунки проводилися методом ZINDO/1 та PM3 в програмі HyperChem. Обговорено питання газообміну за участі гемоглобіну. Розраховані потенціальні криві зв'язування заліза гема з газами СО, СО 2 і О 2. Вперше показана можливість утворення комплексу для моделі гема з карбон(IV) оксидом. Відмічена роль верхніх зайнятих МО залізопорфірину і ліганду в формуванні координаційних зв'язків і переносу заряду в комплексі гема з СО 2. Розглянута роль поляризації зарядів в моделі гема при порівнянні СО 2 з іншими газами. Наші квантово-хімічні розрахунки показили, що СО 2 може координуватися до йона заліза в гемоглобіні, хоча його енергія зв'язування значно менша, ніж для комплексу СО з гемоглобіном і становить близько 34,5 ккал/моль.

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Effects of Breath-Holding Tests on PetCO2 and Arterial Blood Oxygenation in Men

Pytel¹,

Коваленко²

2021

Ukr. ž. med. bìol. sportu

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To evaluate the state of external respiration system, breath-holding tests are usually used. However, there are few studies of the peculiarities of the gas exchange in breath-holding with previous hyperventilation. The purpose of the study was to analyze the dynamics of changes in the PetCO2 level and arterial blood oxygenation during breath-holding tests with and without previous hyperventilation in healthy young men. Materials and methods. The СО2 level was recorded in the side stream on the Datex Normocap capnograph (Datex, Finland). This value was recorded for 5 minutes at rest, 5 minutes after half-breath hold, for 5 minutes of regulated breathing with a frequency of 30 cycles per minute, 5 minutes after half-breath hold. The capnogram, atmospheric pressure level and humidity were used to assess the level of СО2 at the end of exhalation (PetCO2), respiratory rate, the ratio of inspiratory duration to expiratory duration (Rie). Statistical processing of the results was performed by parametric methods. According to the method of sigmoid deviation, three groups of individuals were distinguished by the PetCO2 level: I – PetCO2 < 32.7 mmHg, II – PetCO2 – 32.7-36.2 mmHg, III – PetCO2 > 36.2 mmHg. Results and discussion. Breath-holding during the test after hyperventilation was significantly greater than in the first attempt (62.99±3.31 s and 33.78±2.24 s, p <0.001). Visual qualitative and quantitative analysis of capnograms and graphs of arterial blood oxygenation revealed significant inter-individual features of the reactions of these indicators to tests. Therefore, changes in PetCO2 were compared depending on its initial level. After the breath-holding test, the PetCO2 levels on average during the 5-minute recovery reliably decreased in groups II and III compared with I. During the test with hyperventilation, a natural significant increase in its level of reactivity was registered, most pronounced in group III (-13.48 mmHg, p <0.001). After the second breath-holding, there was a decrease in PetCO2 compared to the level after the first breath-holding in all groups. However, the level of HbO2 in the tests differed only in group II. Thus, after a breath-holding test, individuals with relatively low PetCO2 did not have its decrease in contrast to those with relatively medium and high levels. The use of hyperventilation potentiates these reactions before breath-holding, and aligns their level after a long recovery period in different groups. Conclusion. The study shows that breath-holding tests without and after hyperventilation significantly affect the level of CO2 stress and arterial blood oxygenation; the breath-holding test after hyperventilation potentiates the decrease in PetCO2 and HbO2 in arterial blood by increasing breath-holding time. There are significant individual features in the reactivity of such physiological parameters

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The therapeutic possibilities of carboxytherapy for psoriasis

Cited by 3 publications

References 5 publications

An overview of the role of carboxytherapy in dermatology

An overview of the role of carboxytherapy in dermatology

Interaction of Myoglobin Model with Ligands of Gas Exchange

Effects of Breath-Holding Tests on PetCO2 and Arterial Blood Oxygenation in Men

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