The therapeutic validity and effectiveness of physiotherapeutic exercise following total hip arthroplasty for osteoarthritis: A systematic review

Wijnen, Annet; Bouma, Sietske; Seeber, Gesine H; Woude, L.H.V. van der; Bulstra, Sjoerd K.; Lazovic, Djordje; Stevens, Martin J.; Akker‐Scheek, Inge van den

doi:10.1371/journal.pone.0194517

Cited by 42 publications

(42 citation statements)

References 49 publications

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“…Experimental evidence in animal models has indicated attenuation in cardioprotective pathways with aging, yet information regarding myocardial dysfunction in old age is limited. Similar data are available regarding age-related changes in the human heart [18][19][20]. Resveratrol also dose-dependently increases SIRT1/PGC1α levels ( Figure 2).…”

Section: Discussionsupporting

confidence: 75%

Combination Exercise Regimen and Resveratrol Intake Can Be Considered For Cardiac Rejuvenation Therapy in the Aging Process

Wu¹

2018

Cardiol Vasc Res

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Aging is an inevitable process of life. Become progressively disorganized and degraded with age occurring as a consequence of physiological aging. This process has many different exercise regime or supplementary resveratrol intake molecular biology mechanisms to regulate different aging grade. Indeed, their combination in the molecular biology interaction is our intriguing in this study. We purchased natural aging mice and gene type senescenceaccelerated SAMP8 mice to examine different molecular biology interaction of survival and apoptosis signaling after exercise training, supplementary resveratrol intake, and combination. Histological pathophysiology of age-related cardiac disease was examined using hematoxylin-eosin and Masson's trichrome staining. Apoptosis cells were determined using TUNEL staining. Results showed PGC-1α and SIRT-1 increased were observed in natural aging after exercise training and supplementary resveratrol intake (p<0.05). In the genetic type of genetic senescence-accelerated mice SAMP8, left ventricular weight observed decreased after exercise training, supplementary resveratrol intake, and their combination (p<0.05). However, TUNEL analysis results showed combination exercise training and supplementary resveratrol intake apoptosis cells has significant decreases (p<0.05). We suggest resveratrol intake can help exercise training therapy age-related cardiac disease.

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Section: Discussionsupporting

confidence: 75%

Combination Exercise Regimen and Resveratrol Intake Can Be Considered For Cardiac Rejuvenation Therapy in the Aging Process

Wu¹

2018

Cardiol Vasc Res

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“…The scientific evidence with regard to the effect of sports therapy, especially in the form of joint-specific sports medicine programs, after total joint replacement surgery is scarce (30,31).…”

Section: Discussionmentioning

confidence: 99%

Sports Therapy Interventions Following Total Hip Replacement

Beck

Beyer

Gering³

et al. 2019

Deutsches Ärzteblatt International

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steoarthritis is one of the most common conditions in industrialized nations (1). According to a survey of the Robert Koch Institute conducted in 2010, the lifetime prevalence of degenerative joint disease (osteoarthritis), is 27% for women and 18% for men, with the knee and hip joints being the most common sites (2). Joint replacement is indicated in patients with advanced osteoarthritis of the hip in the presence of relevant functional impairments and joint pain when conservative treatment options have failed. Registry studies have shown that total hip replacement resulted in significant pain reduction, improved day-today functioning and better health-related quality of life (3-6). In many patients, decreases in muscle strength are already noted years before surgery. Exercise physio-Summary Background: Sport rehabilitation is a reimbursable intervention assisting reintegration and self-help. In this study, we measured the effects of sport rehabilitation on muscle strength around the hip joint at 1 year after surgery, as well as cardiopulmonary endurance performance and stability of stance, in patients who had undergone a first implantation of a total hip endoprosthesis (total hip replacement, THR) as a treatment for osteoarthritis of the hip. Methods: 160 patients were randomly allotted either to an intervention group with intensive sport rehabilitation for the first year or to a control group. At three time points (baseline, six and twelve months after surgery), measurements were made of muscular strength around the hip joint (with isokinetic dynamometry), stability of stance, and endurance performance. The primary endpoint was the change in strength of the hip extensors, abductors, flexors, and adductors at twelve months after surgery. Results: With respect to the primary endpoint, the results were not significantly better in patients who had received sport rehabilitation than in those who had not. At one year, the patients in the intervention group had less pain as measured by the WOMAC pain score (p = 0.023), though the size of this effect was small (r = 0.27). Health-related quality of life was higher in the intervention group at six months, albeit with a small effect size (p = 0.036, r = 0.25); this was no longer demonstrable at one year. The other parameters studied displayed no significant changes. Conclusion: This trial did not demonstrate any significant benefit of sports rehabilitation on functional outcomes in patients who had undergone total hip replacement. Nonetheless, positive trends after the intervention were seen in some parameters. The unexpectedly high dropout rate had been underestimated in the planning phase of the trial; further trials with larger numbers of patients should be performed.

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“…A potential limitation of our study is the lack of physical performance measures [ 45 ]. It remains to be seen if inpatient rehabilitation improves gait or strength more so than rehabilitation provided in other settings.…”

Section: Discussionmentioning

confidence: 99%

The effectiveness of inpatient rehabilitation after uncomplicated total hip arthroplasty: a propensity score matched cohort

Naylor

Hart

Mittal

et al. 2018

BMC Musculoskelet Disord

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BackgroundInpatient rehabilitation is an expensive option following total hip arthroplasty (THA). We aimed to determine if THA patients who receive inpatient rehabilitation report better hip and quality of life scores post-surgery compared to those discharged directly home.MethodsProspective, propensity score matched cohort involving 12 private hospitals across five Australian States. Patients undergoing THA secondary to osteoarthritis were included. Those receiving inpatient rehabilitation for reasons other than choice or who experienced significant health events within 90-days post-surgery were excluded. Comparisons were made between those who did and did not receive inpatient rehabilitation for patient-reported hip pain and function (Oxford Hip Score, OHS) and ‘today’ health rating (EuroQol 0–100 scale). Rehabilitation provider charges were also estimated and compared.ResultsTwo hundred forty-six patients (123 pairs, mean age 67 (10) yr., 66% female) were matched on 19 covariates for their propensity to receive inpatient rehabilitation. No statistically nor clinically significant between-group differences were observed [OHS median difference (IQR): 0 (− 3, 3), P = 0.60; 0 (− 1 to 1), P = 0.91, at 90 and 365-days, respectively; EuroQol scale median difference 0 (− 10, 12), P = 0.24; 0 (− 10, 10), P = 0.49; 5 (− 10, 15), P = 0.09, at 35-, 90- and 365-days, respectively]. Median rehabilitation provider charges were 10-fold higher for those who received inpatient rehabilitation [median difference $7582 (5649, 10,249), P < 0.001]. Sensitivity analyses corroborated the results of the primary analyses.ConclusionUtilization of inpatient rehabilitation pathways following THA appears to be low value healthcare. Sustainability of inpatient rehabilitation models may be enhanced if inpatient rehabilitation is reserved for those most impaired or who have limited social supports.Trial registrationClinicalTrials.gov Identifier: NCT01899443.Electronic supplementary materialThe online version of this article (10.1186/s12891-018-2134-3) contains supplementary material, which is available to authorized users.

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The therapeutic validity and effectiveness of physiotherapeutic exercise following total hip arthroplasty for osteoarthritis: A systematic review

Cited by 42 publications

References 49 publications

Combination Exercise Regimen and Resveratrol Intake Can Be Considered For Cardiac Rejuvenation Therapy in the Aging Process

Combination Exercise Regimen and Resveratrol Intake Can Be Considered For Cardiac Rejuvenation Therapy in the Aging Process

Sports Therapy Interventions Following Total Hip Replacement

The effectiveness of inpatient rehabilitation after uncomplicated total hip arthroplasty: a propensity score matched cohort

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