The Thyroid

Winter, William E.; Schatz, Desmond; Bertholf, Roger L.

doi:10.1016/b978-1-4160-6164-9.00055-x

Cited by 4 publications

(3 citation statements)

References 200 publications

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“…In human patients, measurement of circulating TSH (thyrotropin) concentration is now firmly established as the first-line test for assessment of thyroid function in most clinical situations, including hyperthyroidism. 33–35 The finding of a very low serum TSH value is consistent with a diagnosis of hyperthyroidism; if the serum TSH concentration is within the reference interval, then a diagnosis of hyperthyroidism is effectively ruled out. In overt hyperthyroidism, high serum levels of total or free T 4 nearly always accompany a suppressed TSH value, which confirms the diagnosis.…”

Section: Problem 1: Hyperthyroidism Is Suspected But the Cat’s Serum ...mentioning

confidence: 99%

“…30,[36][37][38][39][40] Theoretically, as in people, it could be expected that serum TSH levels would be low in early stages of hyperthyroidism, even before T 4 is clearly elevated. [33][34][35] A recent prospective study provided evidence that an undetectable TSH concentration in euthyroid cats is associated with an increased risk of the subsequent diagnosis of hyperthyroidism. 38 However, it is important to note that almost one-third of all cats had undetectable TSH values at baseline but only half of those cats with low TSH values went on to develop hyperthyroidism.…”

Section: Thyroid-stimulating Hormonementioning

confidence: 99%

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More Than Just T₄

Peterson

2013

Journal of Feline Medicine and Surgery

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Section: Problem 1: Hyperthyroidism Is Suspected But the Cat’s Serum ...mentioning

confidence: 99%

Section: Thyroid-stimulating Hormonementioning

confidence: 99%

More Than Just T₄

Peterson

2013

Journal of Feline Medicine and Surgery

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“…All reagents, calibrators/ standards and patients' specimens were brought to room temperature (20-27ºC). The microplate wells for each calibrator/ standard and patient specimen were formatted, and the following steps described by (Winter, 2012) were taken:…”

Section: Laboratory Proceduresmentioning

confidence: 99%

Serum Levels of Thyroid Hormones in Infertile and Fertile Women Attending a Tertiary Care Hospital in North-Central Nigeria: A Comparative Reproductive Medicine Study

Aliu-Ayo,

Adesina,

Jimoh

et al. 2023

Am. J. Med. Sci. Innov.

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Thyroid hormones have profound effects on reproduction. Normal thyroid function is necessary to maintain reproductive physiology, but its functional abnormalities may cause infertility manifesting as menstrual cycle irregularities. Aim of this research was to determine the serum levels of thyroid hormones in infertile and fertile women attending a tertiary care hospital in North-Central Nigeria. This comparative, reproductive medicine, cross-sectional study was carried out among one hundred and six (106) women attending the Gynecology Clinic of the Department of Obstetrics and Gynecology and the Family Planning Clinic of a tertiary care hospital in North-Central Nigeria. Women with a history suggestive of either primary or secondary infertility and the control women with no history of infertility were evenly grouped. Venous blood samples were collected and analyzed using Enzyme-Linked Immunosorbent Assay (ELISA) technique to determine fT3, fT4 and TSH levels. Data obtained were entered and analyzed using Statistical Package for Social Sciences (SPSS) version 23, and the level of statistical significance was set at p<0.05 and at a confidence interval of 95% for all inferential statistics. Majority (90.6%) of the 106 participants were euthyroid. However, most of the thyroid disorders (80%) were noticed in the infertile women, as 15.1% of them had one form of thyroid disorder. The mean TSH, fT3 and fT4 levels were higher in the infertile patients than in the control group, but the values were still within normal reference range. Mean values of TSH, fT3 and fT4 for the patients and controls were 1.35±1.65 versus 0.85±1.08 mIU/mL, 2.79±1.51 versus 2.19±1.15 pg/mL, and 1.15±0.33 versus 0.99 ± 0.29 ng/dL respectively. Median for TSH, fT3 and fT4 in the patients and controls were as follows: 0.80 (0.40–1.55) versus 0.60 (0.40-0.85) mIU/mL, 2.40 (1.45-4.20) versus 1.70 (1.35-2.95) pg/mL, and 1.10 (1.00-1.30) versus 1.00 (0.90- 1.10) ng/dL respectively. The differences in the median between the patients and controls were statistically significant for fT3 and fT4 with p-values of 0.031 and 0.002 respectively. Subclinical hypothyroidism was the most prevalent (7.5%) thyroid disorder identified in the infertile women. Serum levels of thyroid hormones and prevalence of thyroid disorders were significantly higher in the infertile patients compared to the fertile women, although the overall prevalence of thyroid disorders was quite low.

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The Laboratory Diagnosis of Thyroid Disease

Bailey,

Fitzgerald

2024

Clinical Chemistry

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The Thyroid

Cited by 4 publications

References 200 publications

More Than Just T₄

More Than Just T₄

Serum Levels of Thyroid Hormones in Infertile and Fertile Women Attending a Tertiary Care Hospital in North-Central Nigeria: A Comparative Reproductive Medicine Study

The Laboratory Diagnosis of Thyroid Disease

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The Thyroid

Cited by 4 publications

References 200 publications

More Than Just T4

More Than Just T4

Serum Levels of Thyroid Hormones in Infertile and Fertile Women Attending a Tertiary Care Hospital in North-Central Nigeria: A Comparative Reproductive Medicine Study

The Laboratory Diagnosis of Thyroid Disease

Contact Info

Product

Resources

About

More Than Just T₄

More Than Just T₄