The thyroid gland with low uptake lesions: evaluation by ultrasound.

Solbiati, Luigi; Volterrani, Luca; Rizzatto, G; Bazzocchi, Massimo; Busilacci, P; Candiani, Francesco; Ferrari, Francesca; Giuseppetti, Gianmarco; Maresca, G; Mirk, Paoletta

doi:10.1148/radiology.155.1.3883413

Cited by 132 publications

(90 citation statements)

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“…The ultrasound features of typical papillary carcinoma include an irregular shape, ill-defined margins, a low echoic content, and frequent minute calcification inside the carcinoma (12,13). However, as some papillary carcinomas have a regular shape and are difficult to differentiate from follicular tumors and adenomatous goiter, caution is required (14).…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological characteristics of thyroid cancer misdiagnosed by fine needle aspiration

Maeda

Kutomi

Satomi

et al. 2016

Experimental and Therapeutic Medicine

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Abstract. Fine-needle aspiration (FNA) is commonly used as a preoperative assessment to diagnose thyroid cancer. However, misdiagnosis of malignancy by FNA is not rare, even if image examination suggests the possibility of thyroid cancer. In the present study, the clinicopathological factors of patients whose preoperative FNA examination had not led to a diagnosis of thyroid cancer were examined. In total, 125 patients with thyroid cancer who underwent FNA and surgery (total thyroidectomy, subtotal thyroidectomy or hemithyroidectomy) at the Department of Surgery, Surgical Oncology and Science of the Sapporo Medical University Hospital between 2006 and 2013 were retrospectively analyzed. The patients were divided into two groups: Group A, malignancy determined by FNA, and group B, no malignancy. The groups were then compared by gender, age, tumor size, stage, tumor stage, lymph node metastasis, histology, surgical procedure methods, presence or absence of calcification and thyroglobulin levels. The mean age of the patients in group A (5 males and 59 females) was 53.0 years. The mean age in group B (11 males and 49 females) was 54.2 years. The mean tumor size in both groups was 1.6 cm. The mean thyroglobulin levels were 82.7 ng/ml in Group A and 525.5 ng/ml in group B. There were also significant differences between the groups for tumor stage (P=0.046), histological type (P=0.024) and thyroglobulin levels (P=0.035). The results of the present study suggested that it may be difficult to diagnose thyroid cancer by FNA in cases with non-papillary carcinoma and higher thyroglobulin levels.

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Section: Discussionmentioning

confidence: 99%

Clinicopathological characteristics of thyroid cancer misdiagnosed by fine needle aspiration

Maeda

Kutomi

Satomi

et al. 2016

Experimental and Therapeutic Medicine

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“…Permite valorar tanto el número, la magnitud y las características ecóicas de los nódulos como, utilizando el modo Doppler color, establecer el grado funcional de los mismos y compararlo con el del parénquima circundante. Igualmente, trabajos recientes han demostrado una alta sensibilidad en la discriminación y diagnóstico diferencial de focos de microcarcinoma a través de sus características ecóicas (16,29,30). De esta forma quedan sumadas las ventajas de la ecografía convencional, la CAAF y la gammagrafía en una téc-nica no invasiva y carente de los riesgos de la punción y la irradiación cervical.…”

Section: Discussionunclassified

“…Se da la paradoja de que hoy día la EGB con bocio difuso se diagnostica más frecuentemente por el anatomopatólogo que por el radiólogo (Tabla II). Por ello, estamos de acuerdo con otros autores en la necesidad de fijar un diáme-tro mínimo para que una lesión pueda ser considerada nódulo en la USG; dicha magnitud podría establecerse a partir de valores superiores a los 6-8 mm (15,30).…”

Section: Discussionunclassified

Enfermedad de Graves-Basedow con nódulos tiroideos asociados (enfermedad de Graves-Basedow nodular): Consideraciones clínicas, diagnósticas y terapéuticas

Hernández

Beorlegui

Marco

et al. 2003

An. Med. Interna (Madrid)

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INTRODUCCIÓNLa enfermedad de Graves-Basedow (EGB) se define clásica-mente como un bocio difuso acompañado de hipertirodismo; sin embargo, la experiencia clínica demuestra que con frecuencia se presenta asociado a nódulo/s tiroideo/s. Este fenómeno, que parecía ser característico de los países mediterráneos o con zonas de endemia (1), ha adquirido una gran relevancia en la literatura anglosajona tras la generalización de la ultrasonografía (USG) en los protocolos de estudio del bocio (1,2).19 [0212-7199 (2003) 20: 8; pp 403-409] ANALES DE MEDICINA INTERNA

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“…A grande maioria dos nódulos tireoideanos são sólidos e hipoecogênicos (15). Nódulos com componente cístico geralmente são nódulos colóides (adenomatosos) ou adenomas, que sofrem degeneração císti-co-hemorrágica.…”

Section: Discussionunclassified

Incidentalomas de tiróide: comparação dos achados ultra-sonográficos com o diagnóstico citopatológico

Mazzuco

Canalli

Coral

et al. 2001

Arq Bras Endocrinol Metab

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Arq Bras Endocrinol Metab vol 45 nº 3 Junho 2001 240 RESUMONódulos tireoideanos impalpáveis, descobertos principalmente por ultrasonografia (USG), são denominados "incidentalomas". Sua importância, além da alta prevalência, está na possibilidade da detecção de "carcinoma oculto". Este trabalho objetiva estudar características ultrasonográficas dos incidentalomas de tiróide confrontadas com diagnós-tico citopatológico obtido pela punção-biópsia aspirativa por agulha fina (PBAAF) guiada por USG. Realizou-se um estudo transversal descritivo dos nódulos tireoideanos classificados como "incidentalomas", cujos pacientes, sabidamente portadores dos mesmos por exames prévios, foram submetidos à PBAAF-USG, de janeiro/1996 a maio/1998, em clíni-ca radiológica. Os estudos ultra-sonográfico e citopatológico foram realizados pela mesma equipe médica, considerando-se a citopatologia como padrão-ouro. Nódulos > 1,5cm foram excluídos. No período de estudo, 110 nódulos foram examinados (95 pacientes, alguns portadores de nódulos múltiplos). À citopatologia, 74% dos nódulos eram benignos, 10% malignos e 16% com citodiagnóstico de lesão indeterminada (desconsiderados da análise estatística). Os nódulos malignos apresentaram predomínio das seguintes características à USG: conteú-do sólido (100%), margens irregulares (54%) e microcalcificações (54%), com diferenças estatisticamente significantes dos benignos. Em 72% dos nódulos malignos, havia pelo menos 3 das 5 características indicativas de malignidade: hipoecogenicidade, conteúdo sólido, halo ausente, margem irregular e microcalcificações. A maioria dos incidentalomas estudados foi benigna. As características ultra-sonográficas -conteúdo sólido, margens irregulares e microcalcificações, principalmente quando associadas, devem ser valorizadas ao se investigar malignidade. ABSTRACTThyroid incidentalomas are incidentally found nodules by investigation methods; usually diagnosed by ultrasound (US), which are not evident by palpation. Besides their high prevalence, the possibility of the detection of "occult" carcinoma makes the thyroid incidentalomas an important finding. The aim of the present study was to describe the ultrasonografic features of thyroid incidentalomas according to the cytological diagnosis obtained by US-guided fine-needle aspiration cytology (FNA). A crosssectional study was conducted from January/1996 to May/1998. Ninetyfive patients of a radiologic clinic with a previous finding of incidentaloma were selected and their thyroid nodules were studied (US features and cytological analysis), being considered the cytologic study as gold standard. Nodules > 1.5cm were excluded. In the study period, 110 nodules were examined (95 patients, some of that with multiple nodules), being 74% were benign, 10% malign and 16% of the nodules with cytological diagnoses of uncertain lesion (excluded of the statistical analysis).

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The thyroid gland with low uptake lesions: evaluation by ultrasound.

Cited by 132 publications

References 0 publications

Clinicopathological characteristics of thyroid cancer misdiagnosed by fine needle aspiration

Clinicopathological characteristics of thyroid cancer misdiagnosed by fine needle aspiration

Enfermedad de Graves-Basedow con nódulos tiroideos asociados (enfermedad de Graves-Basedow nodular): Consideraciones clínicas, diagnósticas y terapéuticas

Incidentalomas de tiróide: comparação dos achados ultra-sonográficos com o diagnóstico citopatológico

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