Comparative data .are reported in this paper oni the sugar concentrationls in the fibrous roots (and other parts) of defruited and control cotton plants and the uptake by these plants of bromine, nitrogen, and potassium. The measurements were made 22 days after defruiting (21 days after the addition of bromine to the nutrient solution). The data are discussed in terms of the relation of sugar concentrations in fibrous roots to mineral uptake and the relation of mineral uptake to the growth eyele of the cotton plant.The uptake of soil nutrients by the cotton plant, as shown by WHITE (27), CROWTHER (8,9), DASTUR (10), OLsoN and BLEDSOE (23), and others, proceeds at an inereasing rate through the period of early growth and flowering but subsequently, as the niumber of bolls carried by the plants inereases, the rate of uptake deelilies anid actual losses of mineral elements from the above-ground portions of the plants may-occur. It was suggested a niumber of vears ag,o (8) that the observed reduction in nitrogen uptake during the fruiting period of cotton might be due to depressed root growth. The dominance of fruiting activity over vegetative development and root growth has been well established in cotton (12,13,19, 20) and it seems certain that the extension of roots into new soil zones and the development of new root surfaces would be important factors in solute uptake. The foregoing explanation, however, insufficielntly accounts for all of the known facts. If, on the other hand, fruiting substantially reduces the concentration of sugars in the fibrous roots, the observed reduction in mineral uptake with fruiting can be more fully comprehended.The necessity for an expeniditure of energy for the accumulation of solutes against concentration differenitials has been outlined by HOAGLAND (17) and more recent work with barley seedlings (5) adds assurance that sugars situated in the roots provide the primary respiratory fuel for mineral uptake. It has been shown (18, 20)