Approaching the Ancient Artifact
DOI: 10.1515/9783110308815.127
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The Tombs of Amazons

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“…In 2015, the EPA used Tox21/ToxCast data from 16 assays of early and intermediate molecular events to construct an ER agonist pathway 12,14,1516,17 . These assays target multiple biological processes involved in ER agonistic signaling by measuring receptor binding 18,19 , protein dimerization, transcription factor-DNA interactions, RNA transcript levels 20 , reporter protein levels 21 , and cell proliferation 22 . The goal of this work was to predict and rank the likelihood of ER bioactivity.…”
Section: Introductionmentioning
confidence: 99%
“…In 2015, the EPA used Tox21/ToxCast data from 16 assays of early and intermediate molecular events to construct an ER agonist pathway 12,14,1516,17 . These assays target multiple biological processes involved in ER agonistic signaling by measuring receptor binding 18,19 , protein dimerization, transcription factor-DNA interactions, RNA transcript levels 20 , reporter protein levels 21 , and cell proliferation 22 . The goal of this work was to predict and rank the likelihood of ER bioactivity.…”
Section: Introductionmentioning
confidence: 99%