The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy

Cell stresses occur in a wide variety of settings: in disease, during industrial processes, and as part of normal day‐to‐day rhythms. Adaptation to these stresses requires cells to alter their proteome. Cells modify the proteins they synthesize to aid proteome adaptation. Changes in both mRNA transcription and translation contribute to altered protein synthesis. Here, we discuss the changes in translational mechanisms that occur following the onset of stress, and the impact these have on stress adaptation.

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The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy

Cited by 3 publications

References 67 publications

Nutrient control of growth and metabolism through mTORC1 regulation of mRNA splicing

Nutrient control of growth and metabolism through mTORC1 regulation of mRNA splicing

Stage-specific regulation of undifferentiated spermatogonia by AKT1S1-mediated AKT-mTORC1 signaling during mouse spermatogenesis

Translation regulation in response to stress

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