The Toxic Effect of Gliadin Fractions on the Small Bowel Mucosa of Patients with Coeliac Disease

Abstract

Medical Research Societyhyrlrnlysates t.han from t.hoi r equi vnlent eqiiimolar amino ncid mirt.rirefi, hilt infliience of fit.arter protein composition and hydrolysis method on ahsorption of different hydrolysates has not h e m examined. Tun en7,yme systems, o n e papain hanrd, the othei. a porrine ?ancreat.ir en7,yme nirt.iire were used to prepare partial en7.ymic hydrolyfiates of lactalk~umin (21, eep a1 hiimi n and casein/soy/lactal hiimin mixtiire. Mnleriilar weight profile of all hyrlrnlysates was .55 ,, < 500, 1 yk 5oo-2non. Normal nrrhjerts