“…Cole (1912) also found that saline extracts were sometimes toxic and Neufeld and Dold (1911) demonstrated that extracts made with salt solution which contained 0.1 per cent lecithin were also toxic. Furthermore, saline extracts of pneumonic lungs have been found to be toxic by Rosenow and Arkin (1912), Weiss, Kolmer and Steinfield (1918), and Solis-Cohen, . An extract of the pneumococcus was demonstrated by R-osenow (1907) to have the capacity of decreasing the phagocytosis of avirulent organisms and he also claimed that when avirulent organisms were incubated in this extract for twenty-four hours they became virulent for guinea pigs.…”