The Toxicology of Mercury

Broussard, Larry A.; Hammett‐Stabler, Catherine A.; Winecker, Ruth E.; Ropero‐Miller, Jeri D.

doi:10.1309/5hy1-v3ne-2lfl-p9mt

Cited by 116 publications

(85 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Once in the bloodstream it is rapidly oxidized to mercury(II) in the red blood cells by way of the hydrogen peroxide catalase pathway. 27 This is consistent with the observations that the distribution of elemental mercury in tissues is similar to that observed for mercury(II) salts. The half-life of elemental mercury in the body is reported to be approximately 60 days.…”

Section: Toxicity and Bioaccumulation Of Mercurysupporting

confidence: 91%

“…Approximately 80% of inhaled elemental mercury is absorbed, in contrast with less than 1% absorption after dermal exposure, and almost none (0.1%) after ingestion. 26,27 Mercury vapor is a highly diffusible, monatomic gas. It is soluble in lipids, with a heptane/water partition coefficient of 20.…”

Section: Toxicity and Bioaccumulation Of Mercurymentioning

confidence: 99%

“…The half-life of elemental mercury in the body is reported to be approximately 60 days. 27 Although mercury(I) chloride was used medicinally as a diuretic in the 1800s, very few studies have been reported on the biological effects of mercury(I) compounds. Due to its very low water solubility, mercury(I) chloride was assumed to be poorly absorbed in the gastrointestinal tract.…”

Section: Toxicity and Bioaccumulation Of Mercurymentioning

confidence: 99%

“…30 The half-life of inorganic mercury compounds in the body is reported to be approximately 40 days. 27 The most common organometallic mercury(II) compound in environmental systems is methylmercury. Although inhaled methylmercury is absorbed as efficiently as elemental mercury (80%), the major source of human exposure to methylmercury is ingestion of contaminated fish.…”

Section: Toxicity and Bioaccumulation Of Mercurymentioning

confidence: 99%

See 3 more Smart Citations

In-depth review of atmospheric mercury: sources, transformations, and potential sinks

Gaffney¹,

Marley²

2014

EECT

View full text Add to dashboard Cite

Mercury is a toxic heavy metal that is found naturally throughout the global environment. During the last 100 years, there has been a 70% rise in atmospheric mercury levels over the natural background measured prior to industrialization due to anthropogenic emissions. This increase in mercury levels represents a global threat to the health of ecosystems and humans worldwide. Atmospheric mercury chemistry is complex and its sources and sinks involve equilibrium interactions between the atmosphere, the hydrosphere, and the geosphere. This review outlines the fundamental chemistry of mercury in gas, aqueous, and solid phases, including inorganic, organic, and complexed mercury species. An understanding of this chemistry is important for understanding the cycling between the various environmental compartments as it affects atmospheric loadings. Further, many of these reactions can also occur in the atmosphere in heterogeneous gas/cloud/aerosol interactions. The sources and fate of mercury in the atmosphere, including the cycling of mercury through soil and water as it impacts atmospheric loadings are therefore examined. The sources of major uncertainties in our understanding of mercury in the atmosphere are also discussed, along with recommendations for future studies that include both homogeneous and heterogeneous reactions of the various mercury species.

show abstract

Section: Toxicity and Bioaccumulation Of Mercurysupporting

confidence: 91%

Section: Toxicity and Bioaccumulation Of Mercurymentioning

confidence: 99%

Section: Toxicity and Bioaccumulation Of Mercurymentioning

confidence: 99%

Section: Toxicity and Bioaccumulation Of Mercurymentioning

confidence: 99%

See 2 more Smart Citations

In-depth review of atmospheric mercury: sources, transformations, and potential sinks

Gaffney¹,

Marley²

2014

EECT

View full text Add to dashboard Cite

show abstract

“…Civanın immün sistem üzerine olası etkileri nedeni ile enfeksiyon riskinin arttığı düşünülmektedir. 8,11,16 b b) ) H He em mş şi ir re el li ik k G Gi ir ri iş şi im ml le er ri i: : Hasta hastaneye kabul edildikten kısa süre sonra banyo yolu ile deri arındırma uygulaması yapılmıştır. Deri bütünlüğü izlenmiş, ağız hijyeni için teşvik edilmiş, ağız mukozasının bütünlüğünü korumak için yumuşak diş fırçası temin edilmiş ve hastaya doğru fırçalama öğ-retilmiştir.…”

Section: Hemşi̇reli̇k Tanisiunclassified

Treatment and Nursing Care of the Patient Poisoned by Mercury: Case Report

Kıtış¹,

Palaz²

2015

Turkiye Klinikleri J Nurs

View full text Add to dashboard Cite

Ö ÖZ ZE ET T Tüm formları insan için toksik olan civa elementinin metalik formu yaşam alanlarında kolay ulaşılabilir olması nedeni ile toplum sağlığı açısından önemli bir tehlike oluşturmaktadır. Elemental civanın parlak kurşuni görünümü çocuklar için ilgi çekicidir. Metalik civaya maruz kalanlarda sinir sistemi, cilt, solunum sistemi, kardiyovasküler sistem bulguları görülür. Yüksek düzeyde maruziyette koma ve ölüm görülebilir. Fen bilgisi dersinde civa kavanozunun kırılması sonucu sınıfta bulunan 30 öğrencide zehirlenme belirtileri ortaya çıkmıştır. Bu çalışmada, deri ve solunum yolu ile metalik civaya maruz kalan 14 yaşındaki kız öğrencinin hastaneye kabulü, tedavisi ve bu süreç-teki hemşirelik bakımı ele alınmıştır. Olgu sunumuna konu olan hastanın hastaneye kabulünde vücut ağırlığı 47,5 kg, vücut ısısı 36,6 °C, tansiyonu 100/60 mmHg oksijen satürasyonu %96 idi. Kan fosfor düzeyi 4,9 mg/dL, idrarda civa 43 mg/gün bulundu. Halsizlik, iştahsızlık, baş ve karın ağ-rısı, bulantı ve bulanık görme şikâyetleri olan hastaya, "2,3 dimercapto-1-propanesulfonic acid (DMPS)" ile şelasyon tedavisi uygulandı. Hasta, klinik tablonun düzelmesi üzerine 10. günde taburcu edildi. Sonuç olarak, okul sağlığı hemşiresi bulunan okullarda, okul sağlığı hemşirelerinin ya da toplum sağlığı merkezi hemşirelerinin öğretmenleri, öğrencileri ve ebeveynleri civanın zararları ve korunma konusunda bilgilendirmeleri ve okullarda bulunan civaların uygun şekilde uzaklaştı-rılması önemlidir. Bu çalışmanın amacı, civa zehirlenmesinin belirtileri yanı sıra, tedavi ve hemşi-relik bakımı konusunda hemşirelerin farkındalığını artırmaktır.A An na ah ht ta ar r K Ke el li im me el le er r: : Civa zehirlenmesi; hemşirelik bakımı; şelasyon tedavisi; olgu sunumları A AB BS ST TR RA AC CT T Thanks to its easy accessibility, metallic forms of mercury all, of which are poisonous for human-beings are greatly dangerous for public health. Shiny leaden appearance of it is interesting to children. The ones that are exposed by metallic form of mercury have findings in their neural system, skin, respiratory system, cardiovascular system. In the case of metallic mercury exposure in high level, it could end up with coma and death. In a science lesson, after a mercury container shattered, it emerged that 30 students have poisoning symptom. In this article, hospital admission, treatment and nursing care of a 14 years old girl who was exposure by metallic mercury through the skin and the respiratory passage is discussed. On the admission day her weight was 47.5 kg, her body temperature was 36.6°C, TA 100/60 mmHg and her oxygen saturation was 96%. And phosphorus in blood and mercury in urine were found out 4.9 mg/dL and 43 mg/day respectively. Chelating was treated by DMPS (2,3 Dimercapto-1-propanesulfonic acid) to the patient had lassitude, lack of appetite, headache, stomach-ache and blurred vision. Since clinical signs were eliminated, she discharged on the tenth day. The main reason behind why I choose this topic is pointing out the importance of informing teachers,...

show abstract

Emerging Therapeutic Radiopharmaceuticals and Their Theranostic Pairs

Carbo-Bague

Ramogida

2021

Encyclopedia of Inorganic and Bioinorganic Chemistry

View full text Add to dashboard Cite

Nuclear medicine is a rapidly evolving multidisciplinary research field that has been intensively investigated in the past decades. The successful clinical application of various metal‐based radiopharmaceuticals for cancer imaging and therapy is based on the modular assembly of the drug complex through the popular bifunctional chelate (BFC) strategy. In targeted radionuclide therapy (TRT), potent radiation is selectively delivered to the cancer cells using radiopharmaceuticals that incorporate therapeutic radiometals which emit α ‐particles, β − ‐particles, or Meitner–Auger electrons (MAEs). Radiotheranostics is an emerging concept that connects nuclear imaging (via positron emission tomography (PET) or single‐photon emission computed tomography (SPECT)) and therapy for personalized cancer diagnosis and treatment. This article outlines the fundamentals of radiopharmaceutical design and radiotheranostics and presents a general description of the therapeutic emissions accompanied by literature examples of the most promising radionuclides; 212 Pb, 213 Bi, 225 Ac, 227 Th, and 149 Tb for α therapy; 47 Sc, 67 Cu, 77 As, and 161 Tb for β − therapy; and 119 Sb, 135 La, and 197m/g Hg for MAE therapy. A comparison of the currently used or proposed theranostic pairs of each radiometal is presented.

show abstract

The Toxicology of Mercury

Cited by 116 publications

References 24 publications

In-depth review of atmospheric mercury: sources, transformations, and potential sinks

In-depth review of atmospheric mercury: sources, transformations, and potential sinks

Treatment and Nursing Care of the Patient Poisoned by Mercury: Case Report

Emerging Therapeutic Radiopharmaceuticals and Their Theranostic Pairs

Contact Info

Product

Resources

About