The traditional Chinese medicine Banxia Houpo Tang improves swallowing reflex

Iwasaki, Katsunori; Wang, Q.; Nakagawa, Toshiaki; Suzuki, Toshihiko; Sasaki, Hidetada

doi:10.1016/s0944-7113(99)80043-9

Cited by 61 publications

(45 citation statements)

References 12 publications

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“…Second, certain previous studies have suggested that GERD may be a major factor of SLT (7,8). By contrast, other studies did not support GERD as an etiology of SLT (9). In the present study, there was efficacy of hangekobokuto in 4 of the 7 patients who had been prescribed a proton pump inhibitor or H2 antagonist.…”

Section: Discussioncontrasting

confidence: 72%

“…Improvement of the swallowing function may be associated with their increased cerebral levels (9,11). Hangekobokuto is well-known in North-East Asia for its effective treatment of psychological characteristics, stress and pressure of psychiatric disorder as well as bronchial asthma and impairment of swallowing reflex (9,12). Our previous study reported the successful treatment of an elderly patient with bronchial asthma (6).…”

Section: Discussionmentioning

confidence: 97%

“…Hangekobokuto modulates cerebral levels of 5-hydroxytryptamine, noradrenaline, dopamine and substance-P (9,11). Improvement of the swallowing function may be associated with their increased cerebral levels (9,11). Hangekobokuto is well-known in North-East Asia for its effective treatment of psychological characteristics, stress and pressure of psychiatric disorder as well as bronchial asthma and impairment of swallowing reflex (9,12).…”

Section: Discussionmentioning

confidence: 99%

“…In addition, certain studies suggested that bronchial asthma (6), and gastroesophageal reflux disease (GERD) may be major factors of SLT (7,8). Hangekobokuto (Tsumura Co., Tokyo, Japan), one of the traditional herbal medicines that has been developed by Zhang Zhongjing, a well-known physician of traditional Chinese medicine in the third century, is known as an effective drug on SLT in North-East Asia (9). Treating SLT by hangekobokuto has been previous studied, for example in Jin Gui Yao Lue (a classic clinical book of essential prescriptions of traditional Chinese medicine written by Zhang Zhongjing in the third century).…”

Section: Introductionmentioning

confidence: 99%

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Effect of a traditional herbal medicine, hangekobokuto, on the sensation of a lump in the throat in patients with respiratory diseases

et al. 2016

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Abstract. The sensation of a lump in the throat (SLT) is not a rarely encountered symptom. The etiology of SLT appears to be multifactorial, and the psychological characteristics, stress and pressure of a psychiatric disorder may be significant factors in SLT. Hangekobokuto, one of the traditional herbal medicines, is a known drug that has an effect on SLT. The efficacy of a short-term hangekobokuto treatment on SLT was evaluated. To assess whether a 2-week prescription of hangekobokuto improves SLT mainly in patients with respiratory diseases, a retrospective study was performed between April 2013 and August 2015. During the study period, a total of 43 patients were treated with hangekobokuto. Twelve (27.9%) of the 43 patients were reported to experience completely effective treatment (SLT completely disappeared), and 14 (32.6%) experienced moderately effective treatment (25-99% SLT disappeared). Patients with bronchial asthma and those without a medical history of respiratory disease exhibited a good response to hangekobokuto. No specific predictive factor of the response to hangekobokuto on SLT was identified in the multivariate regression analysis. Therefore, the present results suggested that hangekobokuto could be one of the treatment choices for uncontrolled SLT.

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Section: Discussioncontrasting

confidence: 72%

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effect of a traditional herbal medicine, hangekobokuto, on the sensation of a lump in the throat in patients with respiratory diseases

et al. 2016

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“…4) As for this aspiration pneumonia, depletion of substance P in the pharynx caused disorders of the swallowing reflex. 7) In other reports, capsaicin improved swallowing reflex in patients with cerebral thrombosis or dementia due to cerebral arterial sclerosis.…”

mentioning

confidence: 99%