The transition of alcohol control in China 1990-2019: Impacts and recommendations

Hu, Aqian; Jiang, Heng; Dowling, Rowan; Guo, Lei; Zhao, Xin; Hao, Wei; Xiang, Xiaojun

doi:10.1016/j.drugpo.2022.103698

Cited by 27 publications

(14 citation statements)

References 37 publications

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“…That might be attributed to alcohol consumption in adolescents, which is an emerging problem in China and may lead to an increasing incidence of alcohol-associated liver cancer in young people. 16 , 29 …”

Section: Discussionmentioning

confidence: 99%

“… 32 Finally, in China, alcohol abuse in adolescents is still a common and an emerging problem, and compared with female, males consume more alcohol. 29 , 33 , 34 Thirdly, tobacco smoking is an attributable cause of liver cancer mortality, national smoking surveys in China reported that the prevalence of smoking was higher in males than that in females. 23 …”

Section: Discussionmentioning

confidence: 99%

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Mortality Burden of Liver Cancer in China: An Observational Study From 2008 to 2020

Liu,

Wang,

Wang

et al. 2024

J Clin Transl Hepatol

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Background and Aims: China accounts for nearly half of liver cancer deaths globally. A better understanding of the current liver cancer mortality will be helpful to establishing priorities for intervention and to decreasing the disease burden of liver cancer. The study aimed to explore and predict the mortality burden of liver cancer in China. Methods: Data were extracted from the Disease Surveillance Point system of the Chinese Center for Disease Control and Prevention from 2008 to 2020. Crude and age-standardized liver cancer mortality rates were reported by sex, urban or rural residence, and region. Trends in liver cancer mortality rates from 2008 to 2020 were estimated as average annual percentage change (AAPC). The changing trend of live cancer mortality in the future is also predicted. Results: In 2020, the crude mortality of liver cancer was 25.57/100,000, and males and people lived in rural areas had higher age-standardized liver cancer mortality rates than females and people lived in people in urban areas. Crude mortality and age-standardized mortality rates in southwest provinces (Guangxi, Sichuan, Tibet) and in a northeast province (Heilongjiang) were higher than that in other provinces, and age-specific mortality rates increased with age. From 2008 to 2020, liver cancer mortality rates decreased, but people under 50 years of age had a higher AAPC than those over 50 years of age, possibly because of the adoption of hepatitis B virus vaccination in newborns and children. Furthermore, the mortality of liver cancer in 2021-2030 is predicted to have a downward trend. Conclusions: Liver cancer mortality rates declined in China from 2008 to 2020. Future interventions to control liver cancer mortality need to focus on people of male sex, older age, and living in rural areas or less developed provinces.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Mortality Burden of Liver Cancer in China: An Observational Study From 2008 to 2020

Liu,

Wang,

Wang

et al. 2024

J Clin Transl Hepatol

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“…Alcohol is the most widely used addictive substance in the world, and China’s alcohol market has become one of the world’s largest ( 1 ). People with harmful drinking patterns often suffer from alcohol use disorder (AUD) that impairs health and functioning ( 2 ).…”

Section: Introductionmentioning

confidence: 99%

The effects of BDNF rs6265 and FGF21 rs11665896 polymorphisms on alcohol use disorder-related impulsivity in Han Chinese adults

Yang,

Wang,

Sun

et al. 2024

Front. Psychiatry

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IntroductionPatients with alcohol use disorder (AUD) often experience repeated withdrawal. Impulsivity is the most relevant factor influencing successful withdrawal. Brain-derived neurotrophic factor (BNDF) and fibroblast growth factor 21 (FGF21) are associated with impulsivity. Previous studies on the differential effects of BDNF or FGF21 on impulsivity have focused on single-gene effects and have inconsistent results. We aim to investigate the effects of BDNF rs6265 and FGF21 rs11665896, individually and together, on impulsivity during alcohol withdrawal in patients with AUD.MethodsWe recruited 482 adult Han Chinese males with AUD and assessed their impulsivity using the Barratt Impulsivity Scale. Genomic DNA was extracted and genotyped from peripheral blood samples. Statistical analysis was conducted on the data.ResultsThe T-test and 2 × 2 analysis of variance were used to investigate the effects of the genes on impulsivity. There was a significant BDNF × FGF21 interaction on no-planning impulsiveness (F = 9.15, p = 0.003, η2p = 0.03). Simple main effects analyses and planned comparisons showed that BDNF rs6265 A allele × FGF21 rs11665896 T allele was associated with higher no-planning impulsiveness. Finally, hierarchical regression analyses revealed that only the interaction of BDNF and FGF21 accounted for a significant portion of the variance in no-planning impulsiveness.Conclusion and significanceThe combination of BDNF rs6265 A allele and FGF21 rs11665896 T allele may increase impulsivity and discourage alcohol withdrawal. Our study provides a possible genetic explanation for the effects of associated impulsivity in patients with AUD from the perspective of gene-gene interactions.

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“…( Wu et al, 2022 ) Meanwhile, the tobacco and alcohol industries take advantage of such cultural norms by promoting their products as ‘facilitators’ or ‘proof’ for friendships, social bonds and business partnerships. ( Hu et al, 2022 ) A recent study found that around 97% of current smokers reported sharing and 90% reported gifting cigarettes in China. ( Liao et al, 2022 ) Due to the social and cultural context of smoking and drinking, one may hypothesize that retirement may result in changes in both behaviors due to different social prompts, pressure, and reinforcement for smoking and drinking.…”

Section: Introductionmentioning

confidence: 99%

Retirement transition and smoking and drinking behaviors in older Chinese adults: Analysis from the CHARLS study

Luo,

Bauman,

Phongsavan

et al. 2023

Preventive Medicine Reports

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The transition of alcohol control in China 1990-2019: Impacts and recommendations

Cited by 27 publications

References 37 publications

Mortality Burden of Liver Cancer in China: An Observational Study From 2008 to 2020

Mortality Burden of Liver Cancer in China: An Observational Study From 2008 to 2020

The effects of BDNF rs6265 and FGF21 rs11665896 polymorphisms on alcohol use disorder-related impulsivity in Han Chinese adults

Retirement transition and smoking and drinking behaviors in older Chinese adults: Analysis from the CHARLS study

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