In the last decades, the unstoppable growth of global immigrant entrepreneurs (IE) due to new technology increased IE's mobility and need to create a more rapid flow of expansion. Recent interviews with Chinese entrepreneurs unveiled a network of global channels (guanxi) sustaining their entrepreneurial activities. Despite controversy and critique of some negative aspects of guanxi, scholars concluded that guanxi are the main factor in immigrant-entrepreneur organizations (IEO) global success. The striking resemblance between guanxi and the constructal design in the constructal law started this research about the constructal theory as scientific explanation of guanxi. The fact-based investigation reveals that guanxi extend today like branches of a tree going from immigrant entrepreneurs' country of origin (where IE were born and raised) to their adopted country (where IE now live and work). Today, guanxi are also morphing and expanding in new countries, where other IE-sharing the same culture and language-conduct business. The morphing composition of guanxi includes diverse people, from suppliers and distributors to bankers and partners. Past research praised this marketing system, yet there was no understanding of guanxi design being based on a scientific concept. This paper explores for the first time the connection between successful immigrant channels and the constructal law. World maps, recent surveys and interviews with global entrepreneurs show that the flow of guanxi is real, and the successful outcomes are based on science rather than ingenuity. There is no doubt that guanxi are a real, vivid illustration of the constructal law. In opening new doors and asking new questions, the impact of this research might prove to be substantial.