The Treatment of Acute Coronary Thrombosis

Levine, Samuel A.

doi:10.1001/jama.1932.02740730001001

Cited by 43 publications

(13 citation statements)

References 4 publications

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“…Early mobilization after uncomplicated acute myocardial infarction was proposed in 1951. 24 Before this, patients were prescribed 6 to 8 weeks of bed rest to allow time for myocardial healing and scar formation. 25 Complications of bed rest, together with "harmful psychological effects," prompted a change in approach.…”

Section: Discussionmentioning

confidence: 99%

Inactive and Alone

Bernhardt

Dewey

Thrift

et al. 2004

Stroke

521

218

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Background and Purpose-One way that stroke units may improve outcome is by reducing complications of immobility through early mobilization; however, this intervention needs testing. The purpose of this study was to determine the physical activity patterns of stroke patients managed within acute stroke units as a first step in developing an early mobilization protocol. Methods-We recruited 64 patients within 14 days after stroke from 5 metropolitan stroke units and observed them for 2 consecutive days at 10-minute intervals between the hours of 8 AM and 5 PM. At each observation, we ascertained physical activity, location, and other person(s) present. Therapists recorded therapy details. Results-The 58 patients who completed the study had a mean age of 71.3 years. Stroke severity ranged from mild (National Institutes of Health Stroke Scale score, 1) to severe (score, 27), and mean time after stroke at observation was 5.6 days (range, 0 to 13 days). Only 9 patients were restricted to bed. During the therapeutic day, patients spent Ͼ50% resting in bed, 28% sitting out of bed, and only 13% engaged in activities with the potential to prevent complications and improve recovery of mobility. Patients were alone Ͼ60% of the time. Conclusions-This is the first multicenter study of physical activity early after stroke. We believe the next step is to conduct a randomized controlled trial to evaluate the effect of increased levels of physical activity early after stroke compared with current standards of care.

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Section: Discussionmentioning

confidence: 99%

Inactive and Alone

Bernhardt

Dewey

Thrift

et al. 2004

Stroke

521

218

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“…Early experiments concentrated on the metabolic effects of bed rest and immobilization and documented increased nitrogen excretion (54), calcium loss (6, 71), and decreased glucose tolerance (38). Clinically important side effects of bed rest, including loss of muscle mass and strength, cardiovascular deconditioning, and an increased risk of venous thromboembolism, were recognized during the early 1940s (75,141,203,204 ZERO GRAVITY. Only limited physiological data on the effects of zero gravity were collected during the early phases of the US and USSR manned space-flight programs (261).…”

Section: Experimental Conditionsmentioning

confidence: 99%

Cardiovascular Adjustments to Gravitational Stress

Blomqvist

Stone

1983

Comprehensive Physiology

198

163

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“…Each (1) substantial reduc¬ tion of systolic BP and heart rate at rest and comparable levels of submaximal work; (2) substantial increases in peak oxygen uptake; (3) substantial decreases in myocardial work at rest and submaximal work; (4) substantial changes in body composition, ie, reduced fat and increased muscle mass; (5) taught the Jacobsen relaxation exercises and encouraged to do these at least twice daily. The fifth through 11th sessions were devoted to discussing general areas of stress whether at work, at home, socially, sexually, physically, or in relation to the need to diet, give up smoking, and increase levels of physical activity.…”

mentioning

confidence: 99%

The group counseling v exercise therapy study. A controlled intervention with subjects following myocardial infarction

Stern¹

1983

Archives of Internal Medicine

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One hundred six postmyocardial infarction subjects who either achieved a mean work load of less than seven mets on treadmill testing, who were rated as anxious and/or depressed, or who met both criteria, participated in a controlled study comparing the rehabilitation effectiveness of exercise therapy and group counseling. Each intervention lasted 12 weeks. Follow-up evaluations were scheduled at three months, six months and one year. Exercise substantially increased mean work capacity, decreased fatigue, lessened anxiety and depression, and promoted independence and sociability. Counseling substantially reduced depression and promoted a sense of friendliness, and decreased interpersonal friction as well as greater independence and sociability. The control group reported no substantial change on any measured factor. Neither counseling nor exercise had an effect on mortality though subjects in the exercise group reported fewer major cardiovascular sequelae.

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The Treatment of Acute Coronary Thrombosis

Cited by 43 publications

References 4 publications

Inactive and Alone

Inactive and Alone

Cardiovascular Adjustments to Gravitational Stress

The group counseling v exercise therapy study. A controlled intervention with subjects following myocardial infarction

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