The Treatment of Acute Hepatic Failure by Porcine Liver Perfusion

Jm, Watts

doi:10.5694/j.1326-5377.1969.tb116961.x

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2002

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Cited by 6 publications

(2 citation statements)

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“…These series comprised ECLP of 146 patients (Table 3). Again 10 groups performed ECLP in less than 10 but more than five patients [10,44–55], accounting for 54 patients in total (Table 3). The majority of the remaining authors reported only single cases.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Extracorporeal liver perfusion as hepatic assist in acute liver failure: a review of world experience

Pascher

Sauer

Hammer

et al. 2002

Xenotransplantation

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ECLP using pig livers did not surpass the success of conventional intensive care treatment. An additional effect of transgenic expression of human regulators of complement regulation in porcine livers has not yet been proven. ECLP with human livers not suitable for liver transplantation might prove effective and practicable for temporary hepatic support. Bridging to liver transplantation by long-term ECLP using porcine and human livers appears to have comparable efficacy as bioartificial support methods.

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Section: Resultsmentioning

confidence: 99%

“…Severe immunologic complications were reported in five patients. Three patients developed anaphylactic reactions during ECLP [32, 44, 46, 61]. Low platelet counts were reported to occur frequently.…”

Section: Resultsmentioning

confidence: 99%