The Treatment of Lung Cancer After a Thousand Cases

Fa, Hughes; Ce, Eastridge; Be, Greenberg

doi:10.1097/00007611-196506000-00023

Southern Medical Journal

1965

DOI: 10.1097/00007611-196506000-00023

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The Treatment of Lung Cancer After a Thousand Cases

Hughes Fa¹,

Eastridge Ce²,

Greenberg Be³

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1970

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“…A majority of patients with this disease die from it; the five-year survival rate is only about 5 percent.6. '1 8 One reason for this high fatality rate is that many cases of lung cancer are too advanced for a cure to be possible. As significant symptoms tend to occur late in the course of this disease it is necessary to make an early diagnosis by screening persons likely to develop lung cancer in the presymptomatic stage.…”

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Early diagnosis of carcinoma of the lung. Simultaneous screening with chest x-ray and sputum cytology

Grzybowski¹,

Coy²

1970

Cancer

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Two thousand one hundred and twelve male cigarette smokers over the age of 40, who either suffered from chronic bronchitis, showed long standing radiologic abnormalities, or recently recovered from pneumonia—or who showed another factor making them particularly prone to development of cancer of the lung—were screened with sputum cytology and chest x‐ray. Incidence of lung cancer was high: 17 cases (1 in 125 persons screened) were discovered. Eight of these cases were detected by x‐ray alone, 7 by cytology alone, and only 2 by both of these methods. This suggests that these screening techniques are deficient when used alone. Further confirmation of this is derived from investigation of 228 patients who were screened with negative results in 1965—9 of them developed and then succumbed to lung cancer, and at least 5 of them presumably had it at the time of initial screening. In screening programs an effort should be made not to give the participants a false sense of security concerning absence of lung cancer when results of screening tests are negative. Of the 17 cases, 13 died from cancer of the lung and one from another cause. Three are alive and well. The poor survival in this group was due, to an appreciable extent, to the fact that the same selective factors, such as chronic bronchitis, which rendered these patients liable to lung cancer precluded the possibility of surgical treatment.

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mentioning

confidence: 99%

Early diagnosis of carcinoma of the lung. Simultaneous screening with chest x-ray and sputum cytology

Grzybowski¹,

Coy²

1970

Cancer

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The Treatment of Lung Cancer After a Thousand Cases

Cited by 1 publication

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Early diagnosis of carcinoma of the lung. Simultaneous screening with chest x-ray and sputum cytology

Early diagnosis of carcinoma of the lung. Simultaneous screening with chest x-ray and sputum cytology

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